Social determinants of cardiovascular disease

TM Powell-Wiley, Y Baumer, FO Baah… - Circulation …, 2022 - ahajournals.org
Social determinants of health (SDoH), which encompass the economic, social,
environmental, and psychosocial factors that influence health, play a significant role in the …

The impact of neighborhoods on CV risk

AVD Roux, MS Mujahid, JA Hirsch, K Moore, LV Moore - Global heart, 2016 - Elsevier
Cardiovascular disease (CVD) continues to be the leading cause of death and a major
source of health disparities in the Unites States and globally. Efforts to reduce CVD risk and …

Race-ethnicity, poverty, urban stressors, and telomere length in a Detroit community-based sample

AT Geronimus, JA Pearson… - Journal of health …, 2015 - journals.sagepub.com
Residents of distressed urban areas suffer early aging-related disease and excess mortality.
Using a community-based participatory research approach in a collaboration between social …

Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis

JA Smith, W Zhao, X Wang, SM Ratliff, B Mukherjee… - Epigenetics, 2017 - Taylor & Francis
Living in a disadvantaged neighborhood is associated with poor health outcomes even after
accounting for individual-level socioeconomic factors. The chronic stress of unfavorable …

By what molecular mechanisms do social determinants impact cardiometabolic risk?

Y Baumer, MA Pita, AS Baez… - Clinical …, 2023 - portlandpress.com
While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …

Racial discrimination and telomere shortening among African Americans: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

DH Chae, Y Wang, CD Martz, N Slopen, T Yip… - Health …, 2020 - psycnet.apa.org
Objective: Telomeres are protective sequences of DNA cap** the ends of chromosomes
that shorten over time. Leukocyte telomere length (LTL) is posited to reflect the replicative …

Neighborhood deprivation, racial segregation and associations with cancer risk and outcomes across the cancer-control continuum

BF Fuemmeler, J Shen, H Zhao, R Winn - Molecular psychiatry, 2023 - nature.com
The racial/ethnic disparities in cancer incidence and outcome are partially due to the
inequities in neighborhood advantage. Mounting evidences supported a link between …

Neighborhood disadvantage and biological aging biomarkers among breast cancer patients

J Shen, BF Fuemmeler, VB Sheppard, HD Bear… - Scientific Reports, 2022 - nature.com
Living in a disadvantaged neighborhood is associated with adverse clinical outcomes
among breast cancer patients, but the underlying pathway is still unclear. Limited evidence …

Contribution of life course circumstances to the acceleration of phenotypic and functional aging: a retrospective study

X Cao, C Ma, Z Zheng, L He, M Hao, X Chen… - …, 2022 - thelancet.com
Background Accelerated aging leads to increasing burdens of chronic diseases in late life,
posing a huge challenge to the society. With two well-developed aging measures (ie …

Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study

Z Liu, X Chen, TM Gill, C Ma, EM Crimmins… - PLoS …, 2019 - journals.plos.org
Background An individual's rate of aging directly influences his/her susceptibility to morbidity
and mortality. Thus, quantifying aging and disentangling how various factors coalesce to …