Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …

Diabetes mellitus type 2, a chronic metabolic disease, has globally increased in incidence
and prevalence throughout the lifespan due to the rise in obesity and sedentary lifestyle. The …

Background Exosomes are natural nanoparticles that are involved in intercellular
communication via transferring molecular information between cells. Recently, exosomes …

Abstract Urinary Extracellular Vesicles (uEV) have emerged as a source for biomarkers of
kidney damage, holding potential to replace the conventional invasive techniques including …

Podocyte injury is a key event in the initiation of Diabetic nephropathy (DN).
Tubulointerstitium, especially the proximal tubule has been regarded as a target of injury. In …

Extracellular vesicles (EV s) are nanosized, membrane‐bound vesicles released from
different cells. Recent studies have revealed that EV s may participate in renal tissue …

In this study, we verified the hypothesis that Raman signature of urinary extracellular
vesicles (UEVs) can be used to stratify patients with diabetes at various stages of chronic …

Background: Levels of urinary microvesicles, which are increased during various kidney
injuries, have diagnostic potential for renal diseases. However, the significance of urinary …

Diabetes is the leading cause of kidney disease that progresses to kidney failure. However,
the key molecular and cellular pathways involved in diabetic kidney disease (DKD) …

Background Diabetic nephropathy (DN) is a leading cause of renal failure, whereas the
effective and early diagnostic biomarkers are still lacking. Methods Fourteen cytokines and …