Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

Advanced strategies to thwart foreign body response to implantable devices

S Capuani, G Malgir, CYX Chua… - Bioengineering & …, 2022 - Wiley Online Library
Mitigating the foreign body response (FBR) to implantable medical devices (IMDs) is critical
for successful long‐term clinical deployment. The FBR is an inevitable immunological …

Functional hydrogel interface materials for advanced bioelectronic devices

Q Yang, Z Hu, JA Rogers - Accounts of Materials Research, 2021 - ACS Publications
Conspectus A frontier area of modern research focuses on emerging classes of implantable
bioelectronic devices with unique modes of operation that are relevant both to research …

[HTML][HTML] Smart materials for smart healthcare–moving from sensors and actuators to self-sustained nanoenergy nanosystems

FA Hassani, Q Shi, F Wen, T He, A Haroun… - Smart Materials in …, 2020 - Elsevier
Smart materials offer a significant role in on our lives covering various sensing and actuation
applications in healthcare due to their responsivity to external stimuli such as stress, light …

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

DG Barone, A Carnicer-Lombarte… - Proceedings of the …, 2022 - National Acad Sciences
Fibrotic scarring secondary to the foreign body reaction (FBR) generates a physical barrier
obstructing the functional interaction of implantable medical devices with the host tissue. The …

Modulating the foreign body response of implants for diabetes treatment

BN Kharbikar, GS Chendke, TA Desai - Advanced drug delivery reviews, 2021 - Elsevier
Diabetes Mellitus is a group of diseases characterized by high blood glucose levels due to
patients' inability to produce sufficient insulin. Current interventions often require implants …

Foreign body response to synthetic polymer biomaterials and the role of adaptive immunity

TR Kyriakides, HJ Kim, C Zheng, L Harkins… - Biomedical …, 2022 - iopscience.iop.org
Implanted biomaterials elicit a series of distinct immune and repair-like responses that are
collectively known as the foreign body reaction (FBR). These include processes involving …

3D bioelectronics with a remodellable matrix for long‐term tissue integration and recording

AJ Boys, A Carnicer‐Lombarte… - Advanced …, 2023 - Wiley Online Library
Bioelectronics hold the key for understanding and treating disease. However, achieving
stable, long‐term interfaces between electronics and the body remains a challenge …

Compliant peripheral nerve interfaces

V Paggi, O Akouissi, S Micera… - Journal of neural …, 2021 - iopscience.iop.org
Peripheral nerve interfaces (PNIs) record and/or modulate neural activity of nerves, which
are responsible for conducting sensory-motor information to and from the central nervous …

Low‐voltage soft actuators for interactive human–machine interfaces

S Chen, MWM Tan, X Gong… - Advanced Intelligent …, 2022 - Wiley Online Library
Soft electrical actuators driven by low voltages are promising for interactive human–machine
interfaces (iHMI) applications including executing orders to complete various tasks and …