Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

Type-2-cell-mediated immunity, rich in eosinophils, basophils, mast cells, CD4+ T helper 2
(Th2) cells, and type 2 innate lymphoid cells (ILC2s), protects the host from helminth …

Increases in eosinophil numbers are associated with infection and allergic diseases,
including asthma, but there is also evidence that eosinophils contribute to homeostatic …

Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

The two major lineages of classical dendritic cells (cDCs) express and require either IRF8 or
IRF4 transcription factors for their development and function. IRF8-dependent cDCs promote …

IgE-associated food allergy affects approximately 3% of the population and has severe
effects on the daily life of patients—manifestations occur not only in the gastrointestinal tract …

The intestine harbors a large population of resident eosinophils, yet the function of intestinal
eosinophils has not been explored. Flow cytometry and whole-mount imaging identified …

Eosinophils are innate immune cells that, under certain conditions, can be recruited to the
lungs, where they have an incompletely understood role in health and disease. Eosinophils …