Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Ultrasound‐mediated nano‐sized drug delivery systems for cancer treatment: Multi‐scale and multi‐physics computational modeling

F Moradi Kashkooli, TK Hornsby… - Wiley …, 2024 - Wiley Online Library
Computational modeling enables researchers to study and understand various complex
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …

Multiphysics modeling of low-intensity pulsed ultrasound induced chemotherapeutic drug release from the surface of gold nanoparticles

TK Hornsby, FM Kashkooli, A Jakhmola, MC Kolios… - Cancers, 2023 - mdpi.com
Simple Summary In targeted chemotherapy, ultrasound can be used to induce the release of
anticancer drugs from nanoparticle drug carriers. Our previous study found that after …

[HTML][HTML] Drug Release via Ultrasound-Activated Nanocarriers for Cancer Treatment: A Review

KA Al Refaai, NA AlSawaftah, W Abuwatfa… - Pharmaceutics, 2024 - mdpi.com
Conventional cancer chemotherapy often struggles with safely and effectively delivering
anticancer therapeutics to target tissues, frequently leading to dose-limiting toxicity and …

Real-time non-invasive control of ultrasound hyperthermia using high-frequency ultrasonic backscattered energy in ex vivo tissue and in vivo animal studies

M Nguyen, A Agarwal, JC Kumaradas… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. A reliable, calibrated, non-invasive thermometry method is essential for thermal
therapies to monitor and control the treatment. Ultrasound (US) is an effective thermometry …

Decorrelated compounding of synthetic aperture ultrasound imaging to detect low contrast thermal lesions induced by focused ultrasound

M Nguyen, N Zhao, Y Xu, JJ Tavakkoli - Ultrasonics, 2023 - Elsevier
Abstract Purpose Decorrelated Compounding (DC) for synthetic aperture ultrasound can
reduce speckle variation in images, suggesting enhanced detectability of low-contrast …

[PDF][PDF] Monitoring Focused Ultrasound Thermal Therapy Using Synthetic Aperture Ultrasound Imaging With Decorrelated Compounding

M Nguyen - 2022 - rshare.library.torontomu.ca
Focused Ultrasound (FUS) therapy can be used to induce therapeutic effects to localized
tissue volumes from a distance while sparing surrounding tissues [3, 4, 23, 32]. FUS …