Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Nanoparticle-based immunotherapy for cancer

K Shao, S Singha, X Clemente-Casares, S Tsai… - ACS …, 2015 - ACS Publications
The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Cytokines as biomarkers of nanoparticle immunotoxicity

M Elsabahy, KL Wooley - Chemical Society Reviews, 2013 - pubs.rsc.org
Nanoscale objects, whether of biologic origin or synthetically created, are being developed
into devices for a variety of bionanotechnology diagnostic and pharmaceutical applications …

Medical applications of nanoparticles in biological imaging, cell labeling, antimicrobial agents, and anticancer nanodrugs

R Singh, HS Nalwa - Journal of biomedical nanotechnology, 2011 - ingentaconnect.com
This article reviews the applications of nanotechnology in the fields of medical and life
sciences. Nanoparticles have shown promising applications from diagnosis to treatment of …

Liposome-based drug delivery systems in cancer immunotherapy

Z Gu, CG Da Silva, K Van der Maaden, F Ossendorp… - Pharmaceutics, 2020 - mdpi.com
Cancer immunotherapy has shown remarkable progress in recent years. Nanocarriers, such
as liposomes, have favorable advantages with the potential to further improve cancer …

The interactions between pristine graphene and macrophages and the production of cytokines/chemokines via TLR-and NF-κB-related signaling pathways

H Zhou, K Zhao, W Li, N Yang, Y Liu, C Chen, T Wei - Biomaterials, 2012 - Elsevier
Graphene may have attractive properties for some biomedical applications, but its potential
adverse biological effects, in particular, possible modulation of immune responses, require …

[HTML][HTML] Azadirachta indica leaves mediated green synthesized copper oxide nanoparticles induce apoptosis through activation of TNF-α and caspases signaling …

A Dey, S Manna, S Chattopadhyay, D Mondal… - Journal of Saudi …, 2019 - Elsevier
Green nanotechnology elucidates highly prioritized anticancer activity. We synthesized
Copper oxide nanoparticles (CuONPs) using leaves of Azadirachta indica (A. indica) plants …

[HTML][HTML] Engineering polymer nanoparticles using cell membrane coating technology and their application in cancer treatments: Opportunities and challenges

K Guo, N **ao, Y Liu, Z Wang, J Tóth, J Gyenis… - Nano Materials …, 2022 - Elsevier
Nanotechnology has revolutionized cancer drug delivery, and recent research continues to
focus on the development of “one-size-fits-all,” ie,“all-in-one” delivery nanovehicles …

Modulation of macrophage functional polarity towards anti-inflammatory phenotype with plasmid DNA delivery in CD44 targeting hyaluronic acid nanoparticles

TH Tran, R Rastogi, J Shelke, MM Amiji - Scientific reports, 2015 - nature.com
The purpose of this study was to modulate macrophage polarity from the pro-inflammatory
M1 to anti-inflammatory M2 phenotype using plasmid DNA (pDNA) expressing interleukin-4 …