Nowadays, bioactive natural products play key roles in drug development due to their safety
profile and strong antioxidant power. Vanillin is a natural phenolic compound found in …

Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

Parkinson's disease is one of the most common neurodegenerative diseases in the elderly.
The motor symptoms occur predominantly due to substantial dopamine depletion, caused by …

The knowledge regarding the neurological and behavioral toxic effects associated with
microplastics (MPs) and heavy metals exposure is still scarce. The present study aimed to …

Fipronil (FIP) is widely used across the world as a broad-spectrum phenylpyrazole
insecticide and veterinary drug. FIP was the insecticide to act by targeting the γ-aminobutyric …

Background Parkinson's disease (PD) is characterized by selective and progressive
dopamine (DA) neuron loss in the substantia nigra and other brain regions, with the …

Aging is a major risk factor for neurodegenerative diseases including Alzheimer's disease
(AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). An unbalanced …

Aging is a major risk factor for neurodegenerative diseases including Alzheimer's disease
(AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). An unbalanced …

Investigations into the cellular and molecular biology of genes that cause inherited forms of
Parkinson's disease, as well as the downstream pathways that they trigger, shed …

Aging promotes accumulation of reactive oxygen/nitrogen species (ROS/RNS) in
cardiomyocytes, which leads to contractile dysfunction and cardiac abnormalities. These …