Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in
maintaining gut health and shows promise for potential therapeutic applications. The …

Akkermansia muciniphila, a mucophilic member of the gut microbiota, protects its host
against metabolic disorders. Because it is genetically intractable, the mechanisms …

Akkermansia muciniphila is a promising next-generation beneficial microbe due to its
natural presence in the mucus layer of the gut, its symbiotic ability to degrade mucus, and its …

Gene-environment interactions shape behavior and susceptibility to depression. However,
little is known about the signaling pathways integrating genetic and environmental inputs to …

The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in
heightened susceptibility to an attaching and effacing pathogen, Citrobacter rodentium …

The cell-envelope of Gram-negative bacteria contains endotoxic lipopolysaccharides (LPS)
that are recognized by the innate immune system via Toll-Like Receptors (TLRs). The …

It has been reported that Akkermansia muciniphila improves host metabolism and reduces
inflammation; however, its potential effects on bile acid metabolism and metabolic patterns …

The initial exposure to pathogens and commensals confers innate immune cells the capacity
to respond distinctively upon a second stimulus. This training capacity might play key …

Background Ruminant gut microbiota are critical in ecological adaptation, evolution, and
nutrition utilization because it regulates energy metabolism, promotes nutrient absorption …

Metabolic diseases are caused by a complex interplay between genetics and the
environment, yet many basic studies guiding our understanding of metabolism are confined …