Does skeletal muscle have an 'epi'‐memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise
Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …
performance, maintaining metabolic function and supporting longevity and healthspan …
C2C12 cell model: its role in understanding of insulin resistance at the molecular level and pharmaceutical development at the preclinical stage
Objectives The myoblast cell line, C2C12, has been utilised extensively in vitro as an
examination model in understanding metabolic disease progression. Although it is …
examination model in understanding metabolic disease progression. Although it is …
Deep Proteomics of Mouse Skeletal Muscle Enables Quantitation of Protein Isoforms, Metabolic Pathways, and Transcription Factors*[S]
Skeletal muscle constitutes 40% of individual body mass and plays vital roles in locomotion
and whole-body metabolism. Proteomics of skeletal muscle is challenging because of highly …
and whole-body metabolism. Proteomics of skeletal muscle is challenging because of highly …
Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake
Advancing age is associated with a progressive loss of skeletal muscle (SkM) mass and
function. Given the worldwide aging demographics, this is a major contributor to morbidity …
function. Given the worldwide aging demographics, this is a major contributor to morbidity …
DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity
Skeletal muscle tissue demonstrates global hypermethylation with age. However,
methylome changes across the time-course of differentiation in aged human muscle derived …
methylome changes across the time-course of differentiation in aged human muscle derived …
Muscle cell‐derived cytokines in skeletal muscle regeneration
Regeneration of the mammalian adult skeletal muscle is a well‐orchestrated process
regulated by multiple proteins and signalling pathways. Cytokines constitute a major class of …
regulated by multiple proteins and signalling pathways. Cytokines constitute a major class of …
The bioactive effects of chicoric acid as a functional food ingredient
Y Peng, Q Sun, Y Park - Journal of Medicinal Food, 2019 - liebertpub.com
Chicoric acid, a hydroxycinnamic acid, has been reported to possess a variety of health
benefits, including antivirus, antioxidant, anti-inflammation, obesity prevention, and …
benefits, including antivirus, antioxidant, anti-inflammation, obesity prevention, and …
Resveratrol promotes myogenesis and hypertrophy in murine myoblasts
A Montesano, L Luzi, P Senesi, N Mazzocchi… - Journal of translational …, 2013 - Springer
Background Nutrigenomics elucidate the ability of bioactive food components to influence
gene expression, protein synthesis, degradation and post-translational modifications …
gene expression, protein synthesis, degradation and post-translational modifications …
Improving physiological relevance of cell culture: the possibilities, considerations, and future directions of the ex vivo coculture model
In vitro models provide an important platform for the investigation of cellular growth and
atrophy to inform, or extend mechanistic insights from, logistically challenging in vivo trials …
atrophy to inform, or extend mechanistic insights from, logistically challenging in vivo trials …
Skeletal muscle cells possess a 'memory'of acute early life TNF-α exposure: role of epigenetic adaptation
Sufficient quantity and quality of skeletal muscle is required to maintain lifespan and
healthspan into older age. The concept of skeletal muscle programming/memory has been …
healthspan into older age. The concept of skeletal muscle programming/memory has been …