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Inflammation: mechanisms, costs, and natural variation
Inflammation is a pervasive phenomenon that operates during severe perturbations of
homeostasis, such as infection, injury, and exposure to contaminants, and is triggered by …
homeostasis, such as infection, injury, and exposure to contaminants, and is triggered by …
An ecosystem approach to understanding and managing within-host parasite community dynamics
Hosts are typically coinfected by multiple parasite species, resulting in potentially
overwhelming levels of complexity. We argue that an individual host can be considered to …
overwhelming levels of complexity. We argue that an individual host can be considered to …
Land use-induced spillover: a call to action to safeguard environmental, animal, and human health
The rapid global spread and human health impacts of SARS-CoV-2, the virus that causes
COVID-19, show humanity's vulnerability to zoonotic disease pandemics. Although …
COVID-19, show humanity's vulnerability to zoonotic disease pandemics. Although …
Wild immunology
In wild populations, individuals are regularly exposed to a wide range of pathogens. In this
context, organisms must elicit and regulate effective immune responses to protect their …
context, organisms must elicit and regulate effective immune responses to protect their …
[HTML][HTML] Diet modulates the relationship between immune gene expression and functional immune responses
Nutrition is vital to health and the availability of resources has long been acknowledged as a
key factor in the ability to fight off parasites, as investing in the immune system is costly …
key factor in the ability to fight off parasites, as investing in the immune system is costly …
An immunological marker of tolerance to infection in wild rodents
Hosts are likely to respond to parasitic infections by a combination of resistance (expulsion
of pathogens) and tolerance (active mitigation of pathology). Of these strategies, the basis of …
of pathogens) and tolerance (active mitigation of pathology). Of these strategies, the basis of …
The ecoimmunology of invasive species
Invasive populations frequently harbour a reduced parasite community compared with their
native counterparts. The loss of regulating enemies may result in re‐allocation of resources …
native counterparts. The loss of regulating enemies may result in re‐allocation of resources …
A novel multi-variate immunological approach, reveals immune variation associated with environmental conditions, and co-infection in the koala (Phascolarctos …
External signs of disease are frequently used as indicators of disease susceptibility.
However, immune profiling can be a more effective indicator to understand how host …
However, immune profiling can be a more effective indicator to understand how host …
Genetic diversity in cytokines associated with immune variation and resistance to multiple pathogens in a natural rodent population
Pathogens are believed to drive genetic diversity at host loci involved in immunity to
infectious disease. To date, studies exploring the genetic basis of pathogen resistance in the …
infectious disease. To date, studies exploring the genetic basis of pathogen resistance in the …
Parasitic nematodes simultaneously suppress and benefit from coccidian coinfection in their natural mouse host
Within-host interactions among coinfecting parasites are common and have important
consequences for host health and disease dynamics. However, these within-host …
consequences for host health and disease dynamics. However, these within-host …