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Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …
complex risk structure thought to be influenced by interactions between genetic variants and …
DNA methylation: a promising approach in management of Alzheimer's disease and other neurodegenerative disorders
Simple Summary DNA methylation is an epigenetic modification of genes which affects
corresponding gene expression. During the developmental stage, embryonic stem cells …
corresponding gene expression. During the developmental stage, embryonic stem cells …
DNA methylation as a mediator of genetic and environmental influences on Parkinson's disease susceptibility: Impacts of alpha-Synuclein, physical activity, and …
Parkinson's disease (PD) is a neurodegenerative disorder with a complex etiology and
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …
Neuroepigenetics of ageing and neurodegeneration-associated dementia: An updated review
Gene expression is tremendously altered in the brain during memory acquisition, recall, and
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …
Genetic variation and pesticide exposure influence blood DNA methylation signatures in females with early-stage Parkinson's disease
Although sex, genetics, and exposures can individually influence risk for sporadic
Parkinson's disease (PD), the joint contributions of these factors to the epigenetic etiology of …
Parkinson's disease (PD), the joint contributions of these factors to the epigenetic etiology of …
An Overview of Epigenetic Changes in the Parkinson's Disease Brain
A Klokkaris, A Migdalska-Richards - International Journal of Molecular …, 2024 - mdpi.com
Parkinson's disease is a progressive neurodegenerative disorder, predominantly of the
motor system. Although some genetic components and cellular mechanisms of Parkinson's …
motor system. Although some genetic components and cellular mechanisms of Parkinson's …
[HTML][HTML] Mitochondrial stress-induced H4K12 hyperacetylation dysregulates transcription in Parkinson's disease
Aberrant epigenetic modification has been implicated in the pathogenesis of Parkinson's
disease (PD), which is characterized by the irreversible loss of dopaminergic (DAergic) …
disease (PD), which is characterized by the irreversible loss of dopaminergic (DAergic) …
Effect of pesticides on phosphorylation of tau protein, and its influence on Alzheimer's disease
ED Torres-Sánchez, GG Ortiz… - World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive and neurodegenerative illness which results in
alterations in cognitive development. It is characterized by loss/dysfunction of cholinergic …
alterations in cognitive development. It is characterized by loss/dysfunction of cholinergic …
[HTML][HTML] Exposure to Metals, Pesticides, and Air Pollutants: Focus on Resulting DNA Methylation Changes in Neurodegenerative Diseases
Individuals affected by neurodegenerative diseases, including Alzheimer's disease (AD),
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), are dramatically …
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), are dramatically …
[HTML][HTML] Molecular and cellular interactions in pathogenesis of sporadic Parkinson disease
LP Dolgacheva, VP Zinchenko… - International Journal of …, 2022 - mdpi.com
An increasing number of the population all around the world suffer from age-associated
neurodegenerative diseases including Parkinson's disease (PD). This disorder presents …
neurodegenerative diseases including Parkinson's disease (PD). This disorder presents …