Breast cancer is among the most common cancers in women, second to skin cancer.
Mammary gland development can influence breast cancer development in later life …

High mobility group A1 (HMGA1) is a nonhistone chromatin structural protein characterized
by no transcriptional activity. It mainly plays a regulatory role by modifying the structure of …

MicroRNAs (miRNAs) are small single-stranded regulatory RNAs that are shown to be
dysregulated in a wide array of human cancers. MiRNAs play critical roles in cancer …

The newly discovered LINC02532 is abnormally expressed in a variety of cancers and
promotes cancer progression. The research proposed to discover the biological and …

Breast cancer treatment has advanced significantly, particularly for estrogen receptor-
positive (ER+) tumors. Tamoxifen, an estrogen antagonist, is widely used; however …

The proinflammatory property of cisplatin is potentially destructive and contributes to the
pathogenesis of acute kidney injury (AKI). The role and upstream regulatory mechanism of …

Introduction: 70% of breast cancer patients have an active estrogen receptor. Tamoxifen
illustrates this therapy, interfering with estrogen's ability to bind to cancer cells. The most …

Background This study aimed to explore key microRNAs (miRNAs) and their effects on
hepatocellular carcinoma (HCC) progression. Methods Key deregulated miRNAs in HCC …

Papillary thyroid cancer (PTC) accounts for about 90% of thyroid cancer. There are
approximately 20%–30% of PTC patients showing disease persistence/recurrence and …

The monolayer (two-dimensional or 2D) cell culture, while widely used, lacks fidelity in
replicating vital cell interactions seen in vivo, leading to a shift toward three-dimensional …