The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

Coronary heart disease (CHD) is closely related to oxidative stress and inflammatory
response and is the most common cardiovascular disease (CVD). Iron is an essential …

Ferroptosis plays an important role in the early stage of myocardial ischemia/reperfusion
(MI/R) injury, which is closely associated with the antioxidant damage of mitochondrial …

Ferroptosis is a novel type of regulated cell death (RCD) discovered in recent years, where
abnormal intracellular iron accumulation leads to the onset of lipid peroxidation, which …

The dysregulation of nuclear factor erythroid 2-related factor 2 (Nrf2) and/or solute carrier
family 7 member 11 (SLC7A11) is believed to contribute to ferroptosis in the hearts suffered …

Ferroptosis is a kind of iron-dependent renewal programmed death. Its main mechanism is
to catalyze the unsaturated fatty acids highly expressed on the cell membrane under the …

As common clinical-pathological processes, wound healing and tissue remodelling
following injury or stimulation are essential topics in medical research. Promoting the …

Neuronal damage after ischemic stroke (IS) is frequently due to ferroptosis, contributing
significantly to ischemic injury. However, the mechanism against ferroptosis in IS remained …

Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated
to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure …