Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …

Abstract Interleukin-8 (IL-8) is a proinflammatory CXC chemokine associated with the
promotion of neutrophil chemotaxis and degranulation. This chemokine activates multiple …

The consequences of prostate cancer metastasis remain severe, with huge impact on the
mortality and overall quality of life of affected patients. Despite the convoluted interplay and …

Despite recent advances in our understanding of the biological behavior of prostate cancer
(PCa), PCa is becoming the most common malignancy in men worldwide. The …

Tumors may be initiated and maintained by a cellular subcomponent that displays stem cell
properties. We have used the expression of aldehyde dehydrogenase as assessed by the …

Persistent infection or chronic inflammation contributes significantly to tumourigenesis and
tumour progression. CXC motif ligand 8 (CXCL8) is a chemokine that acts as an important …

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic
adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from …

Abstract Context Prostate cancer (PCa) is the most common cancer in the adult male, and
benign prostatic hyperplasia (BPH) represents the most frequent urologic diagnosis in …

The chemokine receptor CXCR2 is a key mediator of neutrophil migration that also plays a
role in tumor development. However, CXCR2 influences tumors through multiple …