Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a
most dramatic departure from the native structure of DNA. The present review summarizes …

Peptide nucleic acid (PNA) is a nucleic acid mimic with high specificity and binding affinity to
natural DNA or RNA, as well as resistance to enzymatic degradation. PNA sequences can …

Self-assembled nanostructures that are sensitive to environmental stimuli are promising
nanomaterials for drug delivery. In this class, disulfide-containing redox-sensitive strategies …

Oligonucleotides (ONs) have been envisaged for therapeutic applications for more than
thirty years. However, their broad use requires overcoming several hurdles such as …

Disulfide conjugation invariably remains a key tool in research on nucleic acids. This
versatile and cost-effective method plays a crucial role in structural studies of DNA and RNA …

Peptide nucleic acid (PNA) has become an extremely powerful tool in chemistry and biology.
Although PNA recognizes single‐stranded nucleic acids with exceptionally high affinity and …

The discovery of an ever-expanding plethora of coding and non-coding RNAs with nodal
and causal roles in the regulation of lung physiology and disease is reinvigorating interest in …

Peptide nucleic acids (PNAs) are DNA/RNA mimics extensively used for pharmacological
regulation of gene expression in a variety of cellular and molecular systems, and they have …

Peptide nucleic acids (PNA) are a unique class of synthetic molecules that have a peptide
backbone and can hybridize with nucleic acids. Here, a versatile method has been …

The 6-aminoglucosamine ring of the aminoglycoside antibiotic neomycin B (ring II) was
conjugated to a 16-mer peptide nucleic acid (PNA) targeting HIV-1 TAR RNA. For this …