Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

MicroRNAs (miRNA) are small non-coding RNAs (∼ 22 nt in length) that are known as
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …

Alzheimer disease (AD) is a complex neurodegenerative disorder with no definite treatment.
The expression of miR-29 family is significantly reduced in AD, suggesting a part for the …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause
of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …

Small-molecule and protein/antibody drugs mainly act on genome-derived proteins to exert
pharmacological effects. RNA based therapies hold the promise to expand the range of …

Protein aggregation is classically considered the main cause of neuronal death in
neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration …

Abstract Currently, 5.4 million Americans suffer from AD, and these numbers are expected to
increase up to 16 million by 2050. Despite tremendous research efforts, we still do not have …

Alzheimer's disease (AD) is the most common form of neurodegenerative disease featured
with memory loss and cognitive function impairments. Chronic mitochondrial stress is a vital …

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
heavily burdens healthcare systems worldwide. There is a significant requirement to …

A general hallmark of neurological diseases is the loss of redox homeostasis that triggers
oxidative damages to biomolecules compromising neuronal function. Under physiological …