Utilizing graph machine learning within drug discovery and development
Graph machine learning (GML) is receiving growing interest within the pharmaceutical and
biotechnology industries for its ability to model biomolecular structures, the functional …
biotechnology industries for its ability to model biomolecular structures, the functional …
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers
Drug repurposing is promoted as a cost-and time-effective mechanism for providing new
medicines. Often, however, there is insufficient consideration by academic researchers of …
medicines. Often, however, there is insufficient consideration by academic researchers of …
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review
Endometriosis (EM) is defined as endometrial tissues found outside the uterus. Growth and
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …
Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
Identification of bioactive compounds from Glycyrrhiza glabra as possible inhibitor of SARS-CoV-2 spike glycoprotein and non-structural protein-15: a …
At present, the world is facing a pandemic named as COVID-19, caused by SARS-CoV-2.
Traditional Chinese medicine has recommended the use of liquorice (Glycyrrhiza species) …
Traditional Chinese medicine has recommended the use of liquorice (Glycyrrhiza species) …
Drug repurposing in cancer therapy: influence of patient's genetic background in breast cancer treatment
Cancer is among the leading causes of death worldwide and it is estimated that in 2040
more than 29 million people will be diagnosed with some type of cancer. The most prevalent …
more than 29 million people will be diagnosed with some type of cancer. The most prevalent …
Drug repurposing for cancer therapy
Y **a, M Sun, H Huang, WL ** - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …
health. Despite significant advances in surgical, radiotherapeutic and immunological …
Repurposing drugs for the management of COVID-19
J Cusinato, Y Cau, AM Calvani… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 represents
a serious health issue worldwide, with more than 61 million cases and more than 1.4 million …
a serious health issue worldwide, with more than 61 million cases and more than 1.4 million …
[HTML][HTML] Effective drugs used to combat SARS-CoV-2 infection and the current status of vaccines
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a causal factor of the
coronavirus disease 2019 (COVID-19). Drug repurposing, portraying patented drugs as a …
coronavirus disease 2019 (COVID-19). Drug repurposing, portraying patented drugs as a …
Anti-breast cancer potential of a new xanthine derivative: in silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies
Background The overexpression of VEGFR-2 receptors in breast cancer provides a valuable
approach to anticancer strategies. Targeting VEGFR-2, a new semisynthetic compound (T-1 …
approach to anticancer strategies. Targeting VEGFR-2, a new semisynthetic compound (T-1 …