Nanotechnology for angiogenesis: opportunities and challenges

S Kargozar, F Baino, S Hamzehlou… - Chemical Society …, 2020‏ - pubs.rsc.org
Angiogenesis plays a critical role within the human body, from the early stages of life (ie,
embryonic development) to life-threatening diseases (eg, cancer, heart attack, stroke, wound …

Sulfobutylether-β-cyclodextrin: A functional biopolymer for drug delivery applications

CV Pardeshi, RV Kothawade, AR Markad… - Carbohydrate …, 2023‏ - Elsevier
Sulfobutylether β-cyclodextrin (SBE-β-CD) is a polyanionic cyclic oligosaccharide that
contains glucopyranose units forming a torus ring-like structure. SBE-β-CD is gifted with …

[HTML][HTML] Combretastatins: an overview of structure, probable mechanisms of action and potential applications

GŞ Karatoprak, E Küpeli Akkol, Y Genç, H Bardakcı… - Molecules, 2020‏ - mdpi.com
Combretastatins are a class of closely related stilbenes (combretastatins A),
dihydrostilbenes (combretastatins B), phenanthrenes (combretastatins C) and macrocyclic …

Nanobubbles for therapeutic delivery: Production, stability and current prospects

DVB Batchelor, FJ Armistead, N Ingram… - Current Opinion in …, 2021‏ - Elsevier
Nanobubbles (NBs) have recently garnered widespread attention for their potential use as
dual diagnostic and therapeutic agents. Similar to their micron-sized relatives …

Effect of particle size on the pharmacokinetics and biodistribution of parenteral nanoemulsions

W Fan, Z Yu, H Peng, H He, Y Lu, J Qi, X Dong… - International journal of …, 2020‏ - Elsevier
This study aims to investigate the effect of particle size on the pharmacokinetics and
biodistributions of parenteral blank nanoemulsions (NEs). To monitor intact NEs in vivo, a …

[HTML][HTML] Horizon: Microfluidic platform for the production of therapeutic microbubbles and nanobubbles

RH Abou-Saleh, FJ Armistead… - Review of Scientific …, 2021‏ - pubs.aip.org
Microbubbles (MBs) have a multitude of applications including as contrast agents in
ultrasound imaging and as therapeutic drug delivery vehicles, with further scope for …

Molecular effects of glycerol on lipid monolayers at the gas–liquid interface: impact on microbubble physical and mechanical properties

RH Abou-Saleh, JR McLaughlan, RJ Bushby… - Langmuir, 2019‏ - ACS Publications
The production and stability of microbubbles (MBs) is enhanced by increasing the viscosity
of both the formation and storage solution, respectively. Glycerol is a good candidate for …

Lipid-stabilized double emulsions generated in planar microfluidic devices

L Kong, A Levin, Z Toprakcioglu, Y Xu, H Gang, R Ye… - Langmuir, 2020‏ - ACS Publications
Microemulsions have found a wide range of applications exploiting their chemical and
physical properties. Development of microfluidic-based approaches has allowed for the …

[HTML][HTML] Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, combretastatin A4

A Charalambous, V Mico, LE McVeigh… - … , Biology and Medicine, 2021‏ - Elsevier
The hydrophobicity of a drug can be a major challenge in its development and prevents the
clinical translation of highly potent anti-cancer agents. We have used a lipid-based …

Cytotoxic stilbenes and derivatives as promising antimitotic leads for cancer therapy

C Faustino, AP Francisco, V Isca… - Current Pharmaceutical …, 2018‏ - ingentaconnect.com
The growing incidence of cancer, the toxic side-effects associated with conventional
chemotherapeutic agents and the development of multidrug resistance (MDR) drive the …