Toxoplasma gondii and Plasmodium falciparum are important human pathogens. These
parasites and many of their apicomplexan relatives undergo a complex developmental …

Sexual differentiation of malaria parasites from the asexual blood stage into gametocytes is
an essential part of the life cycle, as gametocytes are the form that is taken up by the …

Cell-cell communication is an important mechanism for information exchange promoting cell
survival for the control of features such as population density and differentiation. We …

Pathogens have to balance transmission with persistence. For Plasmodium falciparum, the
most widespread and virulent malaria parasite, persistence within its human host requires …

Clonally variant expression of surface antigens allows the malaria parasite Plasmodium
falciparum to evade immune recognition during blood stage infection and secure malaria …

STING is an innate immune cytosolic adaptor for DNA sensors that engage malaria parasite
(Plasmodium falciparum) or other pathogen DNA. As P. falciparum infects red blood cells …

Obligate intracellular parasites must efficiently invade host cells in order to mature and be
transmitted. For the malaria parasite Plasmodium falciparum, invasion of host red blood cells …

The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of
infected humans. During each replication cycle, a small proportion of parasites commits to …

Proliferation of Plasmodium falciparum in red blood cells is the cause of malaria and is
underpinned by an unconventional cell division mode, called schizogony. Contrary to model …

Background The post-genomic era of malaria research provided unprecedented insights
into the biology of Plasmodium parasites. Due to the large evolutionary distance to model …