Mechanical regulation of chromatin and transcription
Cells and tissues generate and are exposed to various mechanical forces that act across a
range of scales, from tissues to cells to organelles. Forces provide crucial signals to inform …
range of scales, from tissues to cells to organelles. Forces provide crucial signals to inform …
Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis
R Ogawa - International journal of molecular sciences, 2017 - mdpi.com
Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including
trauma, insect bite, burn, surgery, vaccination, skin piercing, acne, folliculitis, chicken pox …
trauma, insect bite, burn, surgery, vaccination, skin piercing, acne, folliculitis, chicken pox …
The keloid disorder: heterogeneity, histopathology, mechanisms and models
GC Limandjaja, FB Niessen, RJ Scheper… - Frontiers in cell and …, 2020 - frontiersin.org
Keloids constitute an abnormal fibroproliferative wound healing response in which raised
scar tissue grows excessively and invasively beyond the original wound borders. This …
scar tissue grows excessively and invasively beyond the original wound borders. This …
[HTML][HTML] Structure and distribution of an unrecognized interstitium in human tissues
PC Benias, RG Wells, B Sackey-Aboagye, H Klavan… - Scientific reports, 2018 - nature.com
Confocal laser endomicroscopy (pCLE) provides real-time histologic imaging of human
tissues at a depth of 60–70 μm during endoscopy. pCLE of the extrahepatic bile duct after …
tissues at a depth of 60–70 μm during endoscopy. pCLE of the extrahepatic bile duct after …
Keloid research: current status and future directions
CH Tsai, R Ogawa - Scars, burns & healing, 2019 - journals.sagepub.com
Introduction: Keloids and hypertrophic scars are fibroproliferative disorders of the skin that
result from abnormal healing of injured or irritated skin. Multiple studies suggest that genetic …
result from abnormal healing of injured or irritated skin. Multiple studies suggest that genetic …
Keloids and hypertrophic scars
A Knowles, DA Glass - Dermatologic Clinics, 2023 - derm.theclinics.com
Keloids are an exaggerated fibroproliferative response to cutaneous wound healing in
which scar tissue grows excessively and invasively beyond the original wound borders …
which scar tissue grows excessively and invasively beyond the original wound borders …
Aligned lovastatin-loaded electrospun nanofibers regulate collagen organization and reduce scar formation
Z Chen, L **ao, C Hu, Z Shen, E Zhou, S Zhang… - Acta Biomaterialia, 2023 - Elsevier
Excessive scar formation caused by cutaneous injury leads to pruritus, pain, contracture,
dyskinesia, and unpleasant appearance. Functional wound dressings are designed to …
dyskinesia, and unpleasant appearance. Functional wound dressings are designed to …
The spectrum of scarring in craniofacial wound repair
Fibrosis is intimately linked to wound healing and is one of the largest causes of wound-
related morbidity. While scar formation is the normal and inevitable outcome of adult …
related morbidity. While scar formation is the normal and inevitable outcome of adult …
Role of inflammasomes in keloids and hypertrophic scars—lessons learned from chronic diabetic wounds and skin fibrosis
C Huang, R Ogawa - International Journal of Molecular Sciences, 2022 - mdpi.com
Keloids and hypertrophic scars are pathological cutaneous scars. They arise from excessive
wound healing, which induces chronic dermal inflammation and results in overwhelming …
wound healing, which induces chronic dermal inflammation and results in overwhelming …
Keloidal pathophysiology: current notions
C Huang, R Ogawa - Scars, burns & healing, 2021 - journals.sagepub.com
Introduction: Keloids are pathological scars that are notorious for their chronic and relentless
invasion into adjacent healthy skin, with commonly seen post-therapeutic recurrence after …
invasion into adjacent healthy skin, with commonly seen post-therapeutic recurrence after …