This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …

Organ-on-a-chip devices have enabled major breakthroughs in biomedical research, but
they have yet to be successfully translated to the pharmaceutical industry. Traditional …

Understanding how nerves regenerate is an important step towards develo** treatments
for human neurological disease, but investigation has so far been limited to complex …

One advantage of the nematode Caenorhabditis elegans as a model organism is its
suitability for in vivo optical microscopy. Imaging C. elegans often requires animals to be …

We present a lens-free optical tomographic microscope, which enables imaging a large
volume of approximately 15 mm3 on a chip, with a spatial resolution of< 1 μm×< 1 μm×< 3 …

Microscopy, phenoty** and visual screens are frequently applied to model organisms in
combination with genetics. Although widely used, these techniques for multicellular …

The field of micro total analysis systems (μTAS), or “lab on a chip”, has continued to gain
maturity. The importance of μTAS is reflected in both the growing number and the improved …

Since the work of Golgi and Cajal, light microscopy has remained a key tool for
neuroscientists to observe cellular properties. Ongoing advances have enabled new …

This article describes the fabrication of a microfluidic device for the liquid culture of many
individual nematode worms (Caenorhabditis elegans) in separate chambers. Each chamber …

A thorough understanding of nerve regeneration in Caenorhabditis elegans requires
performing femtosecond laser nanoaxotomy while minimally affecting the worm. We present …