Elevated circulating insulin levels are frequently observed in the setting of obesity and early
type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of insulin. Higher …

Natural killer (NK) cells are effective in combating infections and tumors and as such are
tempting for adoptive transfer therapy. However, they are not homogeneous but can be …

Among solid electrolytes, sulfides have been considered as one of the most promising
candidates due to their soft nature and high ionic conductivity. However, the interphase …

Obesity is a multifactorial and complex condition that is characterized by abnormal and
excessive white adipose tissue accumulation, which can lead to the development of …

Hepatocellular carcinoma (HCC) is a cause of several deaths related to cancer worldwidely.
In early stage, curative treatments such as surgical resection, liver transplant and local …

Among all the body fluids, breast milk is one of the richest sources of microRNAs (miRNAs).
MiRNAs packaged within the milk exosomes are bioavailable to breastfeeding infants. The …

The fast technological development, particularly single nucleotide polymorphism array, array-
comparative genomic hybridization, and whole exome sequencing, has led to the discovery …

Long non‐coding RNAs (lncRNAs) take various effects in cancer mostly through sponging
with microRNAs (miRNAs). lncRNA NR2F1‐AS1 is found to promote tumour progression in …

Insulin and Insulin-like growth factors (IGFs) perform key roles during embryonic
development, regulating processes of cell proliferation and survival. The IGF signalling …

The insulin signaling pathway is composed of a large number of molecules that positively or
negatively modulate insulin specific signal transduction following its binding to the cognate …