Monocyte chemoattractant protein-1 (MCP-1): an overview
SL Deshmane, S Kremlev, S Amini… - Journal of interferon & …, 2009 - liebertpub.com
Chemokines constitute a family of chemoattractant cytokines and are subdivided into four
families on the basis of the number and spacing of the conserved cysteine residues in the N …
families on the basis of the number and spacing of the conserved cysteine residues in the N …
HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
Pathways to neuronal injury and apoptosis in HIV-associated dementia
Abstract Human immunodeficiency virus-1 (HIV-1) can induce dementia with alarming
occurrence worldwide. The mechanism remains poorly understood, but discovery in brain of …
occurrence worldwide. The mechanism remains poorly understood, but discovery in brain of …
Central nervous system viral invasion and inflammation during acute HIV infection
V Valcour, T Chalermchai, N Sailasuta… - The Journal of …, 2012 - academic.oup.com
Background. Understanding the earliest central nervous system (CNS) events during human
immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but …
immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but …
The MCP/eotaxin subfamily of CC chemokines
E Van Coillie, J Van Damme, G Opdenakker - Cytokine & growth factor …, 1999 - Elsevier
Migration of leukocytes from the bone marrow to the circulation, the primary lymphoid organs
and inflammatory sites is directed by chemokines and specific receptor interactions. Besides …
and inflammatory sites is directed by chemokines and specific receptor interactions. Besides …
Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders
Brain inflammation is a complex cellular and molecular response to stress, injury or infection
of the CNS in attempt to defend against insults, clear dead and damaged neurons and return …
of the CNS in attempt to defend against insults, clear dead and damaged neurons and return …
Activation of central nervous system inflammatory pathways by interferon-alpha: relationship to monoamines and depression
CL Raison, AS Borisov, M Majer, DF Drake… - Biological …, 2009 - Elsevier
BACKGROUND: Interferon (IFN)-alpha has been used to study the effects of innate immune
cytokines on the brain and behavior in humans. The degree to which peripheral …
cytokines on the brain and behavior in humans. The degree to which peripheral …
Elevated sCD163 in plasma but not cerebrospinal fluid is a marker of neurocognitive impairment in HIV infection
Objective: Here we evaluated whether neurocognitive disorders in HIV-infected individuals
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …
on effective antiretroviral therapy (ART) are associated with persistent monocyte activation …
Current status of chemokines in the adult CNS
A Réaux-Le Goazigo, J Van Steenwinckel… - Progress in …, 2013 - Elsevier
Chemokines–chemotactic cytokines–are small secreted proteins that attract and activate
immune and non-immune cells in vitro and in vivo. It has been suggested that chemokines …
immune and non-immune cells in vitro and in vivo. It has been suggested that chemokines …
HIV-1 infection and cognitive impairment in the cART era: a review
With the introduction of combination antiretroviral therapy AIDS dementia complex or HIV-
associated dementia, as it was termed later, largely disappeared in clinical practice …
associated dementia, as it was termed later, largely disappeared in clinical practice …