Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Cytoskeletal crosstalk in cell migration

S Seetharaman, S Etienne-Manneville - Trends in cell biology, 2020 - cell.com
Cell migration is a highly dynamic process driven by the cytoskeleton, which mainly
comprises the actin microfilaments, microtubules, and intermediate filaments. During …

Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Vimentin and cytokeratin: Good alone, bad together

NA Kuburich, P den Hollander, JT Pietz… - Seminars in cancer …, 2022 - Elsevier
The cytoskeleton plays an integral role in maintaining the integrity of epithelial cells.
Epithelial cells primarily employ cytokeratin in their cytoskeleton, whereas mesenchymal …

Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling

F Cheng, Y Shen, P Mohanasundaram… - Proceedings of the …, 2016 - pnas.org
Vimentin has been shown to be involved in wound healing, but its functional contribution to
this process is poorly understood. Here we describe a previously unrecognized function of …

Cytoskeletal dynamics in epithelial-mesenchymal transition: insights into therapeutic targets for cancer metastasis

A Datta, S Deng, V Gopal, KCH Yap, CE Halim, ML Lye… - Cancers, 2021 - mdpi.com
Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

The roles and regulation of the actin cytoskeleton, intermediate filaments and microtubules in smooth muscle cell migration

DD Tang, BD Gerlach - Respiratory research, 2017 - Springer
Smooth muscle cell migration has been implicated in the development of respiratory and
cardiovascular systems; and airway/vascular remodeling. Cell migration is a polarized …

Vimentin diversity in health and disease

F Danielsson, MKK Peterson, H Caldeira Araújo… - Cells, 2018 - mdpi.com
Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Vimentin in cancer and its potential as a molecular target for cancer therapy

A Satelli, S Li - Cellular and molecular life sciences, 2011 - Springer
Vimentin, a major constituent of the intermediate filament family of proteins, is ubiquitously
expressed in normal mesenchymal cells and is known to maintain cellular integrity and …

Vimentin: Regulation and pathogenesis

D Paulin, A Lilienbaum, S Kardjian, O Agbulut, Z Li - Biochimie, 2022 - Elsevier
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its
important role in stabilizing intracellular structure. Vimentin has been recognized for its …