[HTML][HTML] MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases

H Zhou, Y He, W **ong, S **g, X Duan, Z Huang… - Bioactive materials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

Angiogenic effects and crosstalk of adipose-derived mesenchymal stem/stromal cells and their extracellular vesicles with endothelial cells

S Rautiainen, T Laaksonen, R Koivuniemi - International Journal of …, 2021 - mdpi.com
Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

Adult stem cell therapeutics in diabetic retinopathy

S Gaddam, R Periasamy, R Gangaraju - International journal of molecular …, 2019 - mdpi.com
Diabetic retinopathy (DR), a complication of diabetes, is one of the leading causes of
blindness in working-age adults. The pathology of the disease prevents the endogenous …

Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2Akita mouse

SL Elshaer, W Evans, M Pentecost, R Lenin… - Stem Cell Research & …, 2018 - Springer
Background Early-stage diabetic retinopathy (DR) is characterized by neurovascular
defects. In this study, we hypothesized that human adipose-derived stem cells (ASCs) …

[HTML][HTML] In Vitro Models of Diabetes: Focus on Diabetic Retinopathy

G Galgani, G Bray, A Martelli, V Calderone, V Citi - Cells, 2024 - mdpi.com
Diabetic retinopathy is a major eye complication in patients with diabetes mellitus, and it is
the leading cause of blindness and visual impairment in the world. Chronic hyperglycemia …

Modulation of mesenchymal stem cells for enhanced therapeutic utility in ischemic vascular diseases

SL Elshaer, SH Bahram, P Rajashekar… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells are multipotent stem cells isolated from various tissue sources,
including but not limited to bone marrow, adipose, umbilical cord, and Wharton Jelly …

Recent advances of adipose-tissue-derived mesenchymal stem cell-based therapy for retinal diseases

L Finocchio, M Zeppieri, A Gabai, L Spadea… - Journal of Clinical …, 2023 - mdpi.com
With the rapid development of stem cell research in modern times, stem cell-based therapy
has opened a new era of tissue regeneration, becoming one of the most promising …

Successful fat-only whole breast reconstruction using cultured mature adipocytes and conditioned medium containing MCP-1

H Yanaga, M Koga, H Nishina, Y Tanaka, K Yanaga - Scientific Reports, 2023 - nature.com
A mastectomy is a curative treatment for breast cancer. It causes breast and soft tissue
deficits, resulting in a chest with poor vascularity. Autologous tissue breast reconstruction is …

Mesenchymal stem cell induced Foxp3 (+) Tregs suppress effector T cells and protect against retinal ischemic injury

M Agrawal, PK Rasiah, A Bajwa, J Rajasingh… - Cells, 2021 - mdpi.com
Mesenchymal stem/stromal cells (MSC) are well known for immunomodulation; however, the
mechanisms involved in their benefits in the ischemic retina are unknown. This study tested …

Experiment-based interventions to diabetic retinopathy: present and advances

S Liu, Y Ju, P Gu - International Journal of Molecular Sciences, 2022 - mdpi.com
Diabetic retinopathy is the major blinding disease among working-age populations, which is
becoming more significant due to the growth of diabetes. The metabolic-induced oxidative …