ER as master regulator of membrane trafficking and organelle function
EM Wenzel, LA Elfmark, H Stenmark… - Journal of cell biology, 2022 - rupress.org
The endoplasmic reticulum (ER), which occupies a large portion of the cytoplasm, is the
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …
Axonal endoplasmic reticulum dynamics and its roles in neurodegeneration
The physical continuity of axons over long cellular distances poses challenges for their
maintenance. One organelle that faces this challenge is endoplasmic reticulum (ER); unlike …
maintenance. One organelle that faces this challenge is endoplasmic reticulum (ER); unlike …
[HTML][HTML] Maintaining social contacts: The physiological relevance of organelle interactions
BSC Silva, L DiGiovanni, R Kumar… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …
VAP proteins–from organelle tethers to pathogenic host interactors and their role in neuronal disease
Vesicle-associated membrane protein (VAMP)-associated proteins (VAPs) are ubiquitous
ER-resident tail-anchored membrane proteins in eukaryotic cells. Their N-terminal major …
ER-resident tail-anchored membrane proteins in eukaryotic cells. Their N-terminal major …
[HTML][HTML] New insights into the functions of ACBD4/5-like proteins using a combined phylogenetic and experimental approach across model organisms
Acyl-CoA binding domain-containing proteins (ACBDs) perform diverse but often
uncharacterised functions linked to cellular lipid metabolism. Human ACBD4 and ACBD5 …
uncharacterised functions linked to cellular lipid metabolism. Human ACBD4 and ACBD5 …
How neurons maintain their axons long-term: an integrated view of axon biology and pathology
Axons are processes of neurons, up to a metre long, that form the essential biological cables
wiring nervous systems. They must survive, often far away from their cell bodies and up to a …
wiring nervous systems. They must survive, often far away from their cell bodies and up to a …
Staying in healthy contact: how peroxisomes interact with other cell organelles
Y Sargsyan, S Thoms - Trends in Molecular Medicine, 2020 - cell.com
Peroxisomes share extensive metabolic connections with other cell organelles. Membrane
contact sites (MCSs) establish and maintain such interactions, and they are vital for …
contact sites (MCSs) establish and maintain such interactions, and they are vital for …
Regulation of peroxisomal trafficking and distribution
C Covill-Cooke, VS Toncheva, JT Kittler - Cellular and Molecular Life …, 2021 - Springer
Peroxisomes are organelles that perform a wide range of essential metabolic processes. To
ensure that peroxisomes are optimally positioned in the cell, they must be transported by …
ensure that peroxisomes are optimally positioned in the cell, they must be transported by …
[HTML][HTML] Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation
Peroxisomes are highly dynamic subcellular compartments with important functions in lipid
and ROS metabolism. Impaired peroxisomal function can lead to severe metabolic disorders …
and ROS metabolism. Impaired peroxisomal function can lead to severe metabolic disorders …
Investigating the influences of task demand and reward on cardiac pre-ejection period reactivity during a speech-in-noise task
Objectives: Effort investment during listening varies as a function of task demand and
motivation. Several studies have manipulated both these factors to elicit and measure …
motivation. Several studies have manipulated both these factors to elicit and measure …