Effects of acute Ashwagandha ingestion on cognitive function

D **ng, C Yoo, D Gonzalez, V Jenkins… - International Journal of …, 2022 - mdpi.com
Background: Ashwagandha (Withania somnifera) has been reported to decrease
perceptions of stress, enhance mood, and improve cognitive function. However, it is …

Association between urinary caffeine and caffeine metabolites and stroke in American adults: a cross-sectional study from the NHANES, 2009–2014

J Fan, Y Yuan, X Zhang, W Li, W Ma, W Wang, J Gu… - Scientific Reports, 2023 - nature.com
This study investigates the potential correlation between urinary caffeine levels and the
occurrence of stroke, a serious cerebrovascular disease that can lead to disability or death …

Effects of dietary supplementation of a microalgae extract containing fucoxanthin combined with guarana on cognitive function and gaming performance

M Leonard, J Maury, B Dickerson, DE Gonzalez… - Nutrients, 2023 - mdpi.com
Background: Esports competitive gaming requires selective visual attention, memory, quick
judgment, and an ability to sustain psychomotor performance over time. Fucoxanthin is a …

Paraxanthine enhances memory and neuroplasticity more than caffeine in rats

R Jäger, SA Sawan, M Orrú, GM Tinsley… - Experimental Brain …, 2025 - Springer
Paraxanthine (PXN) is the main metabolite of caffeine (CAF). PXN supplementation has
been shown to increase measures of cognition, memory, reasoning, response time, and …

[HTML][HTML] Effects of Supplementation with a Microalgae Extract from Phaeodactylum tricornutum Containing Fucoxanthin on Cognition and Markers of Health in Older …

C Yoo, J Maury, DE Gonzalez, J Ko, D **ng, V Jenkins… - Nutrients, 2024 - mdpi.com
Phaeodactylum tricornutum (PT) is a microalgae extract that contains fucoxanthin and has
been shown to enhance cognitive function in younger populations. The present study …

Paraxanthine supplementation increases muscle mass, strength, and endurance in mice

R Jäger, M Purpura, SD Wells, K Liao, A Godavarthi - Nutrients, 2022 - mdpi.com
Paraxanthine is a natural dietary ingredient and the main metabolite of caffeine in humans.
Compared to caffeine, paraxanthine exhibits lower toxicity, lesser anxiogenic properties …

Paraxanthine safety and comparison to caffeine

SK Szlapinski, A Charrette, N Guthrie… - Frontiers in …, 2023 - frontiersin.org
Introduction: Caffeine, one of the most ubiquitous ingredients found in beverages and other
ingested food products, has a long history of safe use. As a member of the methylxanthine …

Exploring Partial Structural Disorder in Anhydrous Paraxanthine through Combined Experiment, Solid-State Computational Modelling, and Molecular Docking

JN Latosińska, M Latosińska, J Seliger, V Žagar - Processes, 2023 - mdpi.com
Paraxanthine (PX), a major metabolite of caffeine, a protective agent against Alzheimer's
and Parkinson's disease, and a promising drug for the treatment of post-COVID 2019 …

1-Methylxanthine enhances memory and neurotransmitter levels

R Jäger, S Abou Sawan, M Orrú, GM Tinlsey… - PloS one, 2025 - journals.plos.org
1-Methylxanthine (1-MX) is the major metabolite of caffeine and paraxanthine and might
contribute to their activity. 1-MX is an adenosine receptor antagonist and increases the …

Paraxanthine provides greater improvement in cognitive function than caffeine after performing a 10-km run

C Yoo, D **ng, DE Gonzalez, V Jenkins… - Journal of the …, 2024 - Taylor & Francis
Rationale Intense exercise promotes fatigue and can impair cognitive function, particularly
toward the end of competition when decision-making is often critical for success. For this …