Ecological and efficient alternatives to industrial processes have sparked interest for using
microorganisms and enzymes as biocatalysts. One of the difficulties is finding candidates …

Thermostability is an essential requirement of enzymes in the industrial processes to
catalyze the reactions at high temperatures; thus, enzyme engineering through directed …

INTRODUCTION Over billions of years, organisms and their enzymes have been evolving
and adapting in response to selection pressures from their environments. In particular …

The molecular bases of thermal and cold stability and adaptation, which allow proteins to
remain folded and functional in the temperature ranges in which their host organisms live …

As the most abundant aromatic polymers on the Earth, lignin has great potential to produce
biofuels and aromatic chemicals due to their high carbon content and low oxygen content …

Secreted mixtures of Hypocrea jecorina cellulases are able to efficiently degrade cellulosic
biomass to fermentable sugars at large, commercially relevant scales. H. jecorina Cel7A …

Are there any generalized molecular principles of thermal adaptation? Here, integrating the
concepts of structural bioinformatics, sequence analysis, and classical knot theory, we …

Cellulases from glycoside hydrolase family 5 (GH5) are key endoglucanase enzymes in the
degradation of diverse polysaccharide substrates and are used in industrial enzyme …

Abstract Malate dehydrogenases (MalDHs)(EC. 1.1. 1.37), which are involved in the
conversion of oxaloacetate to pyruvate in the tricarboxylic acid cycle, are a relevant model …

Biomass degrading thermophiles play an indispensable role in building lignocellulose-
based supply chains. They operate at high temperatures to improve process efficiencies and …