Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

[HTML][HTML] Varespladib in the treatment of snakebite envenoming: development history and preclinical evidence supporting advancement to clinical trials in patients …

MR Lewin, RW Carter, IA Matteo, SP Samuel, S Rao… - Toxins, 2022 - mdpi.com
The availability of effective, reliably accessible, and affordable treatments for snakebite
envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin …

Modified lipoproteins induce arterial wall inflammation during atherogenesis

MB Lorey, K Öörni, PT Kovanen - Frontiers in cardiovascular …, 2022 - frontiersin.org
Circulating apolipoprotein B-containing lipoproteins, notably the low-density lipoproteins,
enter the inner layer of the arterial wall, the intima, where a fraction of them is retained and …

Small, dense low-density lipoprotein-cholesterol and atherosclerosis: relationship and therapeutic strategies

X **, S Yang, J Lu, M Wu - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Low-density lipoprotein cholesterol (LDL-C) plays an important role in the formation,
incidence, and development of atherosclerosis (AS). Low-density lipoproteins can be …

From organic and inorganic phosphates to valvular and vascular calcifications

M Bäck, JB Michel - Cardiovascular Research, 2021 - academic.oup.com
Calcification of the arterial wall and valves is an important part of the pathophysiological
process of peripheral and coronary atherosclerosis, aortic stenosis, ageing, diabetes, and …

Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory …

JO Bock, I Ortea - Aging (Albany NY), 2020 - pmc.ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19), caused by an outbreak of the severe acute
respiratory syndrome-coronavirus 2 (SARS-CoV-2) in Wuhan, China, has led to an …

Associations of phase angle with platelet-activating factor metabolism and related dietary factors in healthy volunteers

P Detopoulou, E Fragopoulou, T Nomikos… - Frontiers in …, 2023 - frontiersin.org
Introduction Phase angle (PA) is derived from bioelectrical impedance analysis (BIA). It
reflects cell membrane function and decreases in disease. It is affected by inflammation …

Association Lp‐PLA2 gene polymorphisms with coronary heart disease

S Ma, L Ding, M Cai, L Chen, B Yan, J Yang - Disease Markers, 2022 - Wiley Online Library
Objectives. The study evaluated the association between lipoprotein‐associated
phospholipase A2 (Lp‐PLA2) gene polymorphisms and coronary heart disease (CHD), in …

Research advance of Chinese medicine in treating atherosclerosis: focus on lipoprotein-associated phospholipase A2

L Wang, W Zhang, N Lyu, Y Suo, L Yang, B Yu… - Chinese journal of …, 2024 - Springer
As a serious cardiovascular disease, atherosclerosis (AS) causes chronic inflammation and
oxidative stress in the body and poses a threat to human health. Lipoprotein-associated …

[HTML][HTML] Effect of Lactobacillus rhamnosus hsryfm 1301 Fermented Milk on Lipid Metabolism Disorders in High-Fat-Diet Rats

H Qu, L Zong, J Sang, Y Wa, D Chen, Y Huang, X Chen… - Nutrients, 2022 - mdpi.com
To further explore and improve the mechanism of probiotics to alleviate the disorder of lipid
metabolism, transcriptomic and metabolomic with bioinformatic analysis were combined. In …