The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Serotonin (5-hydroxytryptamine, 5-HT) is acknowledged as a major neuromodulator of
nervous systems in both invertebrates and vertebrates. It has been proposed for several …

Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …

The nutraceuticals market is vast, encompassing many different products with inconsistent
levels of evidence available to support their use. This overview represents a Western …

Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …

Background Neuropathic pain is a common and severely disabling state that affects millions
of people worldwide. Microglial activation in the spinal cord plays a critical role in the …

Accumulated evidence indicates that cannabidiol (CBD), a nonpsychotomimetic and
nonaddictive main component of the Cannabis sativa plant, reverses anxiety-like behavior …

Neuropathic pain can be caused by multiple factors, and its prevalence can reach 10% of
the global population. It is becoming increasingly evident that limited or short-lasting …