Background Previous evidence supports androgen deprivation therapy (ADT) with primary
radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer …

Background and objective: Innovations have improved outcomes in advanced prostate
cancer (PC). Nonetheless, we continue to lack high-level evidence on a variety of topics that …

Background The optimal timing of radiotherapy (RT) after radical prostatectomy for prostate
cancer has been uncertain. RADICALS-RT compared efficacy and safety of adjuvant RT …

Salvage radiotherapy (sRT) after radical prostatectomy (RP) is the standard of care
treatment for prostate cancer (PCa) patients experiencing biochemical recurrence (BCR) …

Background and objective The use and duration of androgen deprivation therapy (ADT) with
postoperative radiotherapy (RT) have been uncertain. RADICALS-HD compared adding no …

Radical prostatectomy is widely used to treat localized prostate cancer; however, 20-50% of
patients will experience disease progression despite surgical management. Management of …

Androgen deprivation therapy (ADT) is a mainstay of treatment management with
radiotherapy for prostate cancer, 1 including for men treated for salvage after prostatectomy …

Current US clinical practice guidelines for advanced prostate cancer management contain
recommendations based on high‐level evidence from randomized controlled trials; …

Over the past few years, a number of randomised controlled trials have been published
addressing the management of patients with biochemical recurrence of prostate cancer post …

Background and purpose Salvage radiotherapy (SRT) is a curative treatment option in
patients with biochemical recurrence after radical prostatectomy (RP). Undetectable prostate …