Vitamin B12 status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls

A Sobczyńska-Malefora, E Delvin… - Critical reviews in …, 2021 - Taylor & Francis
Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …

A novel review of homocysteine and pregnancy complications

C Dai, Y Fei, J Li, Y Shi, X Yang - BioMed research international, 2021 - Wiley Online Library
Homocysteine (Hct) is a substance produced in the metabolism of methionine. It is an
essential type of amino acid gained from the daily diet. Methylenetetrahydrofolate reductase …

Facts and recommendations about total homocysteine determinations: an expert opinion

H Refsum, AD Smith, PM Ueland, E Nexo… - Clinical …, 2004 - academic.oup.com
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

Effects of Folate and Vitamin B12 Deficiencies During Pregnancy on Fetal, Infant, and Child Development

AM Molloy, PN Kirke, LC Brody… - Food and nutrition …, 2008 - journals.sagepub.com
The importance of folate in reproduction can be appreciated by considering that the
existence of the vitamin was first suspected from efforts to explain a potentially fatal …

How strong is the association between maternal thrombophilia and adverse pregnancy outcome?: A systematic review

Z Alfirevic, D Roberts, V Martlew - … Journal of Obstetrics & Gynecology and …, 2002 - Elsevier
Objective: To determine whether inherited and acquired thrombophilias are associated with
adverse obstetric complications. Study Design: A systematic review; studies where women …

Genetics of homocysteine metabolism and associated disorders

S Brustolin, R Giugliani, TM Felix - Brazilian Journal of Medical and …, 2010 - SciELO Brasil
Homocysteine is a sulfur-containing amino acid derived from the metabolism of methionine,
an essential amino acid, and is metabolized by one of two pathways: remethylation or …

Socio‐economic disparities in preterm birth: causal pathways and mechanisms

MS Kramer, L Goulet, J Lydon, L Séguin… - Paediatric and …, 2001 - Wiley Online Library
Preterm birth is the leading cause of infant mortality in industrialised societies. Its incidence
is greatly increased among the socially disadvantaged, but the reasons for this excess are …

[PDF][PDF] Hyperhomocysteinemia and neurologic disorders: a review

R Ansari, A Mahta, E Mallack… - Journal of clinical …, 2014 - synapse.koreamed.org
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated from an essential
amino acid: methionine. Hcy concentrations are maintained dynamically by either a …

Folic acid supplementation in early second trimester and the risk of preeclampsia

SW Wen, XK Chen, M Rodger, RR White… - American journal of …, 2008 - Elsevier
OBJECTIVE: The objective of the study was to evaluate the association between folic acid
supplementation in early second trimester and the risk of develo** preeclampsia. STUDY …

Effect of homocysteine on pregnancy: a systematic review

AN Gaiday, AB Tussupkaliyev… - Chemico-biological …, 2018 - Elsevier
Research purpose was to put together the available pieces of present scientific data and to
close the gap in the knowledge of Hcy levels in pregnancy and its association with some …