[PDF][PDF] Failure to reconstitute CD4+ T-cells despite suppression of HIV replication under HAART

F Aiuti, I Mezzaroma - Aids Rev, 2006 - researchgate.net
HAART in HIV-1-infected individuals has a broad spectrum of clinical outcomes. In the
majority of patients, plasma viral load becomes undetectable and CD4+ T-cells increase …

Advances in Mechanism of HIV-1 Immune Reconstitution Failure: Understanding Lymphocyte Subpopulations and Interventions for Immunological Nonresponders

J Liu, C Ding, Y Shi, Y Wang, X Zhang… - The Journal of …, 2024 - academic.oup.com
In individuals diagnosed with AIDS, the primary method of sustained suppression of HIV-1
replication is antiretroviral therapy, which systematically increases CD4+ T cell levels and …

Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy

PM Flynn, BJ Rudy, SD Douglas… - The Journal of …, 2004 - academic.oup.com
Background. Adolescents represent the fastest growing demographic group of new human
immunodeficiency virus (HIV) infections in the United States. At present, there is little …

The impact of host genetics on HIV infection and disease progression in the era of highly active antiretroviral therapy

J Tang, RA Kaslow - Aids, 2003 - journals.lww.com
Suspicion that host genetic factors determine variability in the course of natural HIV-1
infection deepened throughout the 1980s and early 1990s [1, 2], but only relatively recently …

Hydroxyurea in the treatment of HIV infection: clinical efficacy and safety concerns

J Lisziewicz, A Foli, M Wainberg, F Lori - Drug safety, 2003 - Springer
Data from basic science and clinical studies suggest that hydroxyurea (hydroxycarbamide)-
based regimens are effective treatment options for patients with HIV at various stages of …

Switching HIV treatment in adults based on CD4 count versus viral load monitoring: a randomized, non-inferiority trial in Thailand

G Jourdain, S Le Cœur, N Ngo-Giang-Huong… - PLoS …, 2013 - journals.plos.org
Background Viral load (VL) is recommended for monitoring the response to highly active
antiretroviral therapy (HAART) but is not routinely available in most low-and middle-income …

Comparative impact of suppressive antiretroviral regimens on the CD4/CD8 T-cell ratio: a cohort study

M Masiá, S Padilla, X Barber, M Sanchis, G Terol… - Medicine, 2016 - journals.lww.com
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CD4+ T Cell Count Recovery in HIV Type 1–Infected Patients Is Independent of Class of Antiretroviral Therapy

N Khanna, M Opravil, H Furrer… - Clinical infectious …, 2008 - academic.oup.com
Background. In recent years, treatment options for human immunodeficiency virus type 1
(HIV-1) infection have changed from nonboosted protease inhibitors (PIs) to nonnucleoside …

Low CD4+ T-Cell Levels and B-Cell Apoptosis in Vertically HIV-exposed Noninfected Children and Adolescents

M Miyamoto, SD Pessoa, E Ono… - Journal of tropical …, 2010 - academic.oup.com
Lymphocyte subsets, activation markers and apoptosis were assessed in 20 HIV-exposed
noninfected (ENI) children born to HIV-infected women who were or not exposed to …

Hel** people with HIV/AIDS return to work: A randomized clinical trial.

DJ Martin, RA Chernoff, M Buitron… - Rehabilitation …, 2012 - psycnet.apa.org
Objective: New treatments introduced in the mid-1990s led many people with HIV/AIDS who
previously had been disabled by their disease to contemplate workforce reentry; many …