Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota

W Fusco, MB Lorenzo, M Cintoni, S Porcari… - Nutrients, 2023‏ - mdpi.com
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023‏ - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

J Cong, P Liu, Z Han, W Ying, C Li, Y Yang, S Wang… - Immunity, 2024‏ - cell.com
Concentrations of the secondary bile acid, deoxycholic acid (DCA), are aberrantly elevated
in colorectal cancer (CRC) patients, but the consequences remain poorly understood. Here …

Understanding the role of the gut microbiome in gastrointestinal cancer: A review

D Ağagündüz, E Cocozza, Ö Cemali… - Frontiers in …, 2023‏ - frontiersin.org
Gastrointestinal cancer represents one of the most diagnosed types of cancer. Cancer is a
genetic and multifactorial disease, influenced by the host and environmental factors. It has …

Roseburia intestinalis: A Beneficial Gut Organism From the Discoveries in Genus and Species

K Nie, K Ma, W Luo, Z Shen, Z Yang, M **ao… - Frontiers in Cellular …, 2021‏ - frontiersin.org
Roseburia intestinalis is an anaerobic, Gram-positive, slightly curved rod-shaped flagellated
bacterium that produces butyrate in the colon. R. intestinalis has been shown to prevent …

Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

Y He, L Fu, Y Li, W Wang, M Gong, J Zhang, X Dong… - Cell metabolism, 2021‏ - cell.com
Recent studies in both mice and humans have suggested that gut microbiota could
modulate tumor responsiveness to chemo-or immunotherapies. However, the underlying …

Soluble dietary fiber, one of the most important nutrients for the gut microbiota

ZW Guan, EZ Yu, Q Feng - Molecules, 2021‏ - mdpi.com
Dietary fiber is a widely recognized nutrient for human health. Previous studies proved that
dietary fiber has significant implications for gastrointestinal health by regulating the gut …

Health and disease markers correlate with gut microbiome composition across thousands of people

O Manor, CL Dai, SA Kornilov, B Smith… - Nature …, 2020‏ - nature.com
Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …

[HTML][HTML] The Many Faces of Enterococcus spp.—Commensal, Probiotic and Opportunistic Pathogen

B Krawczyk, P Wityk, M Gałęcka, M Michalik - Microorganisms, 2021‏ - mdpi.com
Enterococcus spp. are Gram-positive, facultative, anaerobic cocci, which are found in the
intestinal flora and, less frequently, in the vagina or mouth. Enterococcus faecalis and …

Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon

C Guo, D Guo, L Fang, T Sang, J Wu, C Guo… - Carbohydrate …, 2021‏ - Elsevier
This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …