Applications and challenges of ultra-small particle size nanoparticles in tumor therapy

J Xu, M Song, Z Fang, L Zheng, X Huang… - Journal of Controlled …, 2023 - Elsevier
With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery

MK Shim, S Yang, IC Sun, K Kim - Advanced Drug Delivery Reviews, 2022 - Elsevier
As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …

[HTML][HTML] Recent advances and clinical translation of liposomal delivery systems in cancer therapy

J Chen, S Hu, M Sun, J Shi, H Zhang, H Yu… - European Journal of …, 2024 - Elsevier
The limitations of conventional cancer treatment are driving the emergence and
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …

Persistent luminescence-activated Janus nanomotors with integration of photodynamic and photothermal cancer therapies

Z Zhang, T **a, P Ran, J Wei, J Meng, G Zhang… - Chemical Engineering …, 2023 - Elsevier
Cancer photothermal (PTT) and photodynamic therapies (PDT) have aroused tremendous
attention with high spatial specificity, but they experience the challenges from the inefficient …

[HTML][HTML] Enhancing RNA-lipid nanoparticle delivery: organ-and cell-specificity and barcoding strategies

PS Wei, N Thota, G John, E Chang, S Lee… - Journal of Controlled …, 2024 - Elsevier
Recent advancements in RNA therapeutics highlight the critical need for precision gene
delivery systems that target specific organs and cells. Lipid nanoparticles (LNPs) have …

Nanoparticle-based adjuvants and delivery systems for modern vaccines

B Filipić, I Pantelić, I Nikolić, D Majhen… - Vaccines, 2023 - mdpi.com
Ever since the development of the first vaccine, vaccination has had the great impact on
global health, leading to the decrease in the burden of numerous infectious diseases …

[HTML][HTML] Advances in delivering oxidative modulators for disease therapy

W Yang, H Yue, G Lu, W Wang, Y Deng, G Ma, W Wei - Research, 2022 - spj.science.org
Oxidation modulators regarding antioxidants and reactive oxygen species (ROS) inducers
have been used for the treatment of many diseases. However, a systematic review that …

Biodegradable polyester-based nano drug delivery system in cancer chemotherapy: a review of recent progress (2021–2023)

Z Wang, M **ao, F Guo, Y Yan, H Tian… - … in Bioengineering and …, 2023 - frontiersin.org
Cancer presents a formidable threat to human health, with the majority of cases currently
lacking a complete cure. Frequently, chemotherapy drugs are required to impede its …

[HTML][HTML] Electrostatic spraying for fine-tuning particle dimensions to enhance oral bioavailability of poorly water-soluble drugs

JS Kim, S Cheon, MR Woo, S Woo, JE Chung… - Asian Journal of …, 2024 - Elsevier
While spray-drying has been widely utilized to improve the bioavailability of poorly water-
soluble drugs, the outcomes often exhibit suboptimal particle size distribution and large …

ZnO-incorporated alginate assemblies: Tunable pH-responsiveness and improved drug delivery for cancer therapy

Y Feng, W Yang, X Shi, X Zhao - International Journal of Biological …, 2024 - Elsevier
Delivering drugs selectively to tumor tissues is a significant challenge in cancer therapy, and
pH-responsive polymeric assemblies have shown great potential in achieving this goal. In …