The pituitary gland represents the hub of our endocrine system. Its cells produce specific
hormones that direct multiple vital physiological processes such as body growth, fertility, and …

The crosstalk between the chromaffin and adrenocortical cells is essential for the endocrine
activity of the adrenal glands. This interaction is also likely important for tumorigenesis and …

Simple Summary The intricate endocrine system regulates human physiology by producing
and secreting various hormones. Novel methodology pertaining to spheroids and organoids …

Background. The dual role of GCs has been observed in breast cancer; however, due to
many concomitant factors, GR action in cancer biology is still ambiguous. In this study, we …

Adrenocortical carcinoma (ACC) is a rare malignancy of the adrenal cortex that is associated
with a poor prognosis. Develo** effective treatment options for ACC is challenging owing …

Acromegaly is a challenging medical condition that arises from the excessive production of
growth hormones and the insulin-like growth factor 1 in the pituitary gland. While surgery is …

1. Centro Universitário de Mineiros (UNIFIMES), Mineiros,(GO), Brasil. 2. Universidade
Federal do Triângulo Mineiro (UFTM), Uberaba,(MG), Brasil. 3. Universidade de São Paulo …

Medullary thyroid carcinoma contributes to about 3–4% of thyroid cancers and affects C cells
rather than follicular cells. Thyroid C cell differentiation from human pluripotent stem cells …

Há muitos anos a cultura celular bidimensional (2D) é utilizada como modelo de estudo de
doenças, possuindo grande importância na medicina regenerativa, apesar de ainda conter …

Specific cues provided to cells by the extracellular matrix (ECM) are determined by its
composition. Except of collagens other naturally occurring ECM components should be …