[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics

Y Gupta, OV Savytskyi, M Coban, A Venugopal… - Molecular Aspects of …, 2023 - Elsevier
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

Bioactive Azadirachta indica and Melia azedarach leaves extracts with anti-SARS-CoV-2 and antibacterial activities

BA Hemdan, A Mostafa, MM Elbatanony, AM El-Feky… - PLoS …, 2023 - journals.plos.org
The leaves of Azadirachta indica L. and Melia azedarach L., belonging to Meliaceae family,
have been shown to have medicinal benefits and are extensively employed in traditional folk …

3-chymotrypsin-like protease in SARS-CoV-2

K Al Adem, JC Ferreira, AJ Villanueva, S Fadl… - Bioscience …, 2024 - portlandpress.com
Coronaviruses constitute a significant threat to the human population. Severe acute
respiratory syndrome coronavirus-2, SARS-CoV-2, is a highly pathogenic human …

Promising Cytotoxic butenolides from the Soybean endophytic fungus Aspergillus terreus: a combined molecular docking and in-vitro studies

SS El-Hawary, AS Moawad, HS Bahr… - Journal of Applied …, 2023 - academic.oup.com
Aim This study aimed to use one strain many compounds approach (OSMAC) to investigate
the cytotoxic potential of Aspergillus terreus associated with soybean versus several cancer …

[HTML][HTML] Molecular docking and dynamics studies show: Phytochemicals from Papaya leaves extracts as potential inhibitors of SARS–CoV–2 proteins targets and TNF …

MS Abd Shukor, MY Abd Shukor - AIMS Molecular Science, 2023 - aimspress.com
Tackling COVID-19 requires halting virus proliferation and reducing viral complications in
humans. Papaya leaf extract (PLE) is well known for its ability to inhibit numerous viral …