Hydrogels for RNA delivery
RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …
genetic level, and some have been approved for clinical use, including the recent COVID-19 …
Skin wound healing assisted by angiogenic targeted tissue engineering: A comprehensive review of bioengineered approaches
Skin injuries and in particular, chronic wounds, are one of the major prevalent medical
problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration …
problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration …
[HTML][HTML] Small extracellular vesicles in combination with sleep-related circRNA3503: a targeted therapeutic agent with injectable thermosensitive hydrogel to prevent …
Osteoarthritis (OA), characterized by chondrocyte apoptosis and disturbance of the balance
between catabolism and anabolism of the extracellular matrix (ECM), is the most common …
between catabolism and anabolism of the extracellular matrix (ECM), is the most common …
[HTML][HTML] Electroactive material-based biosensors for detection and drug delivery
Electroactive materials are employed at the interface of biology and electronics due to their
advantageous intrinsic properties as soft organic electronics. We examine the most recent …
advantageous intrinsic properties as soft organic electronics. We examine the most recent …
[HTML][HTML] Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment
Diabetic foot ulcers (DFUs) are a devastating complication for diabetic patients that have
debilitating effects and can ultimately lead to limb amputation. Healthy wounds progress …
debilitating effects and can ultimately lead to limb amputation. Healthy wounds progress …
A biomimetic, bilayered antimicrobial collagen-based scaffold for enhanced healing of complex wound conditions
Chronic, nonhealing wounds in the form of diabetic foot ulcers (DFUs) are a major
complication for diabetic patients. The inability of a DFU to heal appropriately leads to an …
complication for diabetic patients. The inability of a DFU to heal appropriately leads to an …
Hydrogels as emerging materials for translational biomedicine
Hydrogels have been extensively investigated as biomaterials because of their excellent
biocompatibility, and recent developments such as 3D printing and the incorporation of …
biocompatibility, and recent developments such as 3D printing and the incorporation of …
The influence of polysaccharides‐based material on macrophage phenotypes
Macrophage polarization is a key factor in determining the success of implanted tissue
engineering scaffolds. Polysaccharides (derived from plants, animals, and microorganisms) …
engineering scaffolds. Polysaccharides (derived from plants, animals, and microorganisms) …
Polymer capsules as micro-/nanoreactors for therapeutic applications: Current strategies to control membrane permeability
Polymer capsules, fabricated either with the aid of a sacrificial template or via the self-
assembly of block copolymers into polymer vesicles (polymersomes), have attracted a great …
assembly of block copolymers into polymer vesicles (polymersomes), have attracted a great …
Engineered Hydrogels for Local and Sustained Delivery of RNA‐Interference Therapies
It has been nearly two decades since RNA‐interference (RNAi) was first reported. While
there are no approved clinical uses, several phase II and III clinical trials suggest the great …
there are no approved clinical uses, several phase II and III clinical trials suggest the great …