Stem cells have emerged as the starting material of choice for bioprocesses to produce cells
and tissues to treat degenerative, genetic, and immunological disease. Translating the …

The shortage of organ donors for regenerative medicine has stimulated research on stem
cells as a potential resource for cell-based therapy. Stem cells have been used widely for …

Differences in chromatin organization are key to the multiplicity of cell states that arise from a
single genetic background, yet the landscapes of in vivo tissues remain largely uncharted …

Recent observations on cancer cell metabolism indicate increased serine synthesis from
glucose as a marker of poor prognosis. We have predicted that a fraction of the synthesized …

A hallmark of cancer cells is the metabolic switch from oxidative phosphorylation (OXPHOS)
to glycolysis, a phenomenon referred to as the 'Warburg effect', which is also observed in …

Background The unique features of human embryonic stem (hES) cells make them the best
candidate resource for both cell replacement therapy and development research. However …

Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and
human induced pluripotent stem cells (hiPSCs), provide a new cell source for regenerative …

Molecular markers defining self-renewing pluripotent embryonic stem cells (ESCs) have
been identified by relative comparisons between undifferentiated and differentiated cells …

OBJECTIVE To examine whether gene profiles can provide a molecular evaluation of the
quality and therapeutic potential in patients with myelomeningocele (MM), by comparing …

Background Endothelial differentiation occurs during normal vascular development in the
develo** embryo. This process is recapitulated in the adult when endothelial progenitor …