Tracking placental development in health and disease
Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
Stimuli‐responsive NO release for on‐demand gas‐sensitized synergistic cancer therapy
Featuring high biocompatibility, the emerging field of gas therapy has attracted extensive
attention in the medical and scientific communities. Currently, considerable research has …
attention in the medical and scientific communities. Currently, considerable research has …
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
The role of aspirin, heparin, and other interventions in the prevention and treatment of fetal growth restriction
Fetal growth restriction and related placental pathologies such as preeclampsia, stillbirth,
and placental abruption are believed to arise in early pregnancy when inadequate …
and placental abruption are believed to arise in early pregnancy when inadequate …
Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
LP Wu, D Ahmadvand, J Su, A Hall, X Tan… - Nature …, 2019 - nature.com
The filamentous bacteriophage fd bind a cell target with exquisite specificity through its few
copies of display peptides, whereas nanoparticles functionalized with hundreds to …
copies of display peptides, whereas nanoparticles functionalized with hundreds to …
Near-infrared light-triggered nano-prodrug for cancer gas therapy
Gas therapy (GT) has attracted increasing attention in recent years as a new cancer
treatment method with favorable therapeutic efficacy and reduced side effects. Several gas …
treatment method with favorable therapeutic efficacy and reduced side effects. Several gas …
[HTML][HTML] Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling
X Yang, Y Ding, L Sun, M Shi, P Zhang, Z Huang… - Redox biology, 2022 - Elsevier
The proteomic analysis from samples of patients with preeclampsia (PE) displayed a low
level of ferritin light chains (FTL), but we do not know what the significance of reduced FTL in …
level of ferritin light chains (FTL), but we do not know what the significance of reduced FTL in …
Nanoparticles in pregnancy: the next frontier in reproductive therapeutics
BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …
Multifunctional nano MOF drug delivery platform in combination therapy
D Ma, G Wang, J Lu, X Zeng, Y Cheng, Z Zhang… - European Journal of …, 2023 - Elsevier
Recent preclinical and clinical studies have demonstrated that for cancer treatment,
combination therapies are more effective than monotherapies in reducing drug-related …
combination therapies are more effective than monotherapies in reducing drug-related …
Placental bed research: II. Functional and immunological investigations of the placental bed
Research on the placenta as the interface between the mother and the fetus has been
undertaken for some 150 years, and in 2 subsequent reviews, we attempted to summarize …
undertaken for some 150 years, and in 2 subsequent reviews, we attempted to summarize …