Advances in pathogenesis and therapeutic strategies for osteoporosis
S Song, Y Guo, Y Yang, D Fu - Pharmacology & therapeutics, 2022 - Elsevier
Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …
[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention
R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …
Secondary osteoporosis
PR Ebeling, HH Nguyen, J Aleksova… - Endocrine …, 2022 - academic.oup.com
Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …
[HTML][HTML] Antibiotics for cancer treatment: A double-edged sword
Various antibiotics have been used in the treatment of cancers, via their anti-proliferative,
pro-apoptotic and anti-epithelial-mesenchymal-transition (EMT) capabilities. However …
pro-apoptotic and anti-epithelial-mesenchymal-transition (EMT) capabilities. However …
The human gut microbiota: a key mediator of osteoporosis and osteogenesis
KD Seely, CA Kotelko, H Douglas, B Bealer… - International journal of …, 2021 - mdpi.com
An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …
[HTML][HTML] Gut microbiota and metabolite alterations associated with reduced bone mineral density or bone metabolic indexes in postmenopausal osteoporosis
Reduced bone mineral density (BMD) is associated with an altered microbiota in senile
osteoporosis. However, the relationship among gut microbiota, BMD and bone metabolic …
osteoporosis. However, the relationship among gut microbiota, BMD and bone metabolic …
[HTML][HTML] Engineered bacterial extracellular vesicles for osteoporosis therapy
H Liu, M Li, T Zhang, X Liu, H Zhang, Z Geng… - Chemical Engineering …, 2022 - Elsevier
Osteoporosis (OP) is a systemic bone disease characterized by reduction of bone mass and
destruction of structure, which can easily lead to fragility fractures. Over the past decade, an …
destruction of structure, which can easily lead to fragility fractures. Over the past decade, an …
The microbiota-gut-bone axis and bone health
Y Tu, R Yang, X Xu, X Zhou - Journal of leukocyte biology, 2021 - academic.oup.com
The gastrointestinal tract is colonized by trillions of microorganisms, consisting of bacteria,
fungi, and viruses, known as the “second gene pool” of the human body. In recent years, the …
fungi, and viruses, known as the “second gene pool” of the human body. In recent years, the …
The role of gut microbiota in bone homeostasis
J Behera, J Ison, SC Tyagi, N Tyagi - Bone, 2020 - Elsevier
The gut microbiota (GM) is referred to as the second gene pool of the human body and a
commensal, symbiotic, and pathogenic microorganism living in our intestines. The …
commensal, symbiotic, and pathogenic microorganism living in our intestines. The …
[HTML][HTML] Bone-targeted engineered bacterial extracellular vesicles delivering miRNA to treat osteoporosis
H Liu, Y Wu, F Wang, S Wang, N Ji, M Wang… - Composites Part B …, 2023 - Elsevier
Osteoporosis (OP), characterized by decreased bone density and destruction of bone
microstructure, is a common systemic bone disease in the elderly. Conventional therapies …
microstructure, is a common systemic bone disease in the elderly. Conventional therapies …