Systemic lupus erythematosus pathogenesis: interferon and beyond

S Caielli, Z Wan, V Pascual - Annual review of immunology, 2023 - annualreviews.org
Autoreactive B cells and interferons are central players in systemic lupus erythematosus
(SLE) pathogenesis. The partial success of drugs targeting these pathways, however …

The role of viral infections in the onset of autoimmune diseases

B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

The role of inflammation in autoimmune disease: a therapeutic target

Y ** safe and effective delivery strategies for localizing messenger RNA (mRNA)
payloads to the spleen is an important goal in the field of genetic medicine. Accomplishing …