G protein-coupled receptors (GPCRs), as the largest family of membrane receptors, actively
modulate plasma membrane and endosomal signalling. Importantly, GPCRs are naturally …

The presynaptic dopamine transporter mediates rapid reuptake of synaptic dopamine.
Although cell surface DAT trafficking recently emerged as an important component of DAT …

D2 dopamine receptors (DRD2s) belong to a family of G protein-coupled receptors that
modulate synaptic dopaminergic tone via regulation of dopamine synthesis, storage, and …

The role of lateral mobility and nanodomain organization of G protein-coupled receptors in
modulating subcellular signaling has been under increasing scrutiny. Investigation of D2 …

The serotonin transporter (SERT) is the primary target for selective serotonin reuptake
inhibitor (SSRI) antidepressants that are thought to exert their therapeutic effects by …

Single-molecule imaging has illuminated dynamics and kinetics of neuronal proteins in their
native membranes hel** us understand their effective roles in the brain. Here, we describe …

Single quantum dot tracking (SQDT) is a powerful technique for interrogating biomolecular
dynamics in living cells and tissue. SQDT has particularly excelled in driving discovery at the …

Creation of various photoluminescent nanomaterials has significantly expanded the arsenal
of approaches used in modern biomedicine. Their unique photophysical properties can …

Создание разнообразных наноматериалов, обладающих фотолюминесцентными
свойствами, существенно расширило арсенал подходов, применяемых в современной …

The dopamine transporter (DAT) protein determines strength and duration of
neurotransmission by dopamine reuptake from extracellular space into presynaptic nerve …