In the first 20 years of life, the human brain undergoes tremendous growth in size, weight,
and synaptic connectedness. Over the same time period, a person achieves remarkable …

Executive function develops during adolescence, yet it remains unknown how structural
brain networks mature to facilitate activation of the fronto-parietal system, which is critical for …

Traumatic brain injury (TBI) is a common but heterogeneous injury underpinned by
numerous complex and interrelated pathophysiological mechanisms. An essential trace …

Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation
technique that applies mA currents at the scalp to modulate cortical excitability. Here, we …

Older adults typically show decline in a variety of cognitive functions including inhibitory
control and language production, with corresponding age-related increases in fMRI …

Functional magnetic resonance imaging (fMRI) detects changes in brain activity by
measuring fluctuations in blood oxygenation. This interpretation relies on the mechanism of …

Despite being a popular neuromodulation technique, clinical translation of transcranial
direct current stimulation (tDCS) is hampered by variable responses observed within …

Background: Brain structure, oxygenation and perfusion are important factors in aging.
Coupling between regional cerebral oxygen consumption and perfusion also reflects …

Cerebral blood flow (CBF) is an important hemodynamic parameter to evaluate brain health.
It can be obtained quantitatively using medical imaging modalities such as magnetic …

Cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2) are
physiological parameters that not only reflect brain health and disease but also jointly …