Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

DNA methylation is a broadly-investigated epigenetic modification that has been considered
as a heritable and reversible change. Previous findings have indicated that DNA methylation …

Background Peripheral epigenetic marks hold promise for understanding psychiatric illness
and may represent fingerprints of gene–environment interactions. We conducted an initial …

DNA methylation acts at the interface of genetic and environmental factors relevant for
autism spectrum disorder (ASD). Placenta, normally discarded at birth, is a potentially rich …

Fibromyalgia (FM) is a highly disabling syndrome defined by a low pain threshold and a
permanent state of pain. The mechanisms explaining this complex disorder remain unclear …

Evidence for myelin regulating higher‐order brain function and disease is rapidly
accumulating; however, defining cellular/molecular mechanisms remains challenging …

Leucine-rich repeat and immunoglobulin domain-containing protein (Lingo-1) is a potent
negative regulator of neuron and oligodendrocyte survival, neurite extension, axon …

Glioma is a common and aggressive primary malignant brain tumor. MicroRNAs (miRNAs)
play key roles in the post-transcriptional regulation of gene expression. Currently, miRNAs …

Obesity is a common but highly, clinically, and genetically heterogeneous disease. Deletion
of the terminal region of the short arm of chromosome 2 is rare and has been reported in …

Toward the identification of genetic basis of complex traits, transcriptome-wide association
study (TWAS) is successful in integrating transcriptome data. However, TWAS is only …