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Immune response following traumatic spinal cord injury: Pathophysiology and therapies
RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
High-dose methylprednisolone for acute traumatic spinal cord injury: a meta-analysis
Z Liu, Y Yang, L He, M Pang, C Luo, B Liu, L Rong - Neurology, 2019 - neurology.org
Objective Due to the continuing debates on the utility of high-dose methylprednisolone (MP)
early after acute spinal cord injury (ASCI), we aimed to evaluate the therapeutic and adverse …
early after acute spinal cord injury (ASCI), we aimed to evaluate the therapeutic and adverse …
A clinical practice guideline for the management of patients with acute spinal cord injury: recommendations on the use of methylprednisolone sodium succinate
MG Fehlings, JR Wilson, LA Tetreault… - Global spine …, 2017 - journals.sagepub.com
Introduction: The objective of this guideline is to outline the appropriate use of
methylprednisolone sodium succinate (MPSS) in patients with acute spinal cord injury (SCI) …
methylprednisolone sodium succinate (MPSS) in patients with acute spinal cord injury (SCI) …
Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives
Spinal cord injury (SCI) has a complex pathophysiology. Following the initial physical
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …
Prolonged inflammation leads to ongoing damage after spinal cord injury
JM Kwiecien, W Dabrowski, B Dąbrowska-Bouta… - PloS one, 2020 - journals.plos.org
The pathogenesis of spinal cord injury (SCI) remains poorly understood and treatment
remains limited. Emerging evidence indicates that post-SCI inflammation is severe but the …
remains limited. Emerging evidence indicates that post-SCI inflammation is severe but the …
[HTML][HTML] Clinical neurorestorative therapeutic guidelines for spinal cord injury (IANR/CANR version 2019)
H Huang, W Young, S Skaper, L Chen… - Journal of orthopaedic …, 2020 - Elsevier
Functional restoration after spinal cord injury (SCI) is one of the most challenging tasks in
neurological clinical practice. With a view to exploring effective neurorestorative methods in …
neurological clinical practice. With a view to exploring effective neurorestorative methods in …
Methylprednisolone for the treatment of patients with acute spinal cord injuries: a systematic review and meta-analysis
Previous meta-analyses of methylprednisolone (MPS) for patients with acute traumatic
spinal cord injuries (TSCIs) have not addressed confidence in the quality of evidence used …
spinal cord injuries (TSCIs) have not addressed confidence in the quality of evidence used …
[HTML][HTML] Clinical trials in traumatic spinal cord injury
J Donovan, S Kirshblum - Neurotherapeutics, 2018 - Elsevier
Traumatic spinal cord injury (SCI) results in impaired neurologic function that for many
individuals is permanent and significantly impacts health, function, quality of life, and life …
individuals is permanent and significantly impacts health, function, quality of life, and life …
[HTML][HTML] Milestones and current achievements in development of multifunctional bioscaffolds for medical application
Tissue engineering (TE) is a rapidly growing interdisciplinary field, which aims to restore or
improve lost tissue function. Despite that TE was introduced more than 20 years ago …
improve lost tissue function. Despite that TE was introduced more than 20 years ago …