Biointerface design for vertical nanoprobes

R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Advancing Intelligent Organ‐on‐a‐Chip Systems with Comprehensive In Situ Bioanalysis

X Li, H Zhu, B Gu, C Yao, Y Gu, W Xu… - Advanced …, 2024 - Wiley Online Library
In vitro models are essential to a broad range of biomedical research, such as pathological
studies, drug development, and personalized medicine. As a potentially transformative …

[HTML][HTML] Integrating physicomechanical and biological strategies for BTE: biomaterials-induced osteogenic differentiation of MSCs

H Shi, K Zhou, M Wang, N Wang, Y Song, W **ong… - Theranostics, 2023 - ncbi.nlm.nih.gov
Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …

Insights gained from computational modeling of YAP/TAZ signaling for cellular mechanotransduction

H Jafarinia, A Khalilimeybodi, J Barrasa-Fano… - NPJ systems biology …, 2024 - nature.com
YAP/TAZ signaling pathway is regulated by a multiplicity of feedback loops, crosstalk with
other pathways, and both mechanical and biochemical stimuli. Computational modeling …

Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au‐Nanofiber Matrix Regulates Cytoskeletal‐to‐Nuclear Mechanoresponses and Lineage …

RK Singh, AG Kurian, V Sagar, I Park… - Advanced Functional …, 2023 - Wiley Online Library
Biophysical stimulation regulates stem cell functions, including proliferation and
differentiation. Matrix nanotopography and external forces, such as electromagnetic fields …

Engineering the Cellular Microenvironment: Integrating Three-Dimensional Nontopographical and Two-Dimensional Biochemical Cues for Precise Control of Cellular …

E Sarikhani, DP Meganathan, AKK Larsen… - ACS …, 2024 - ACS Publications
The development of biomaterials capable of regulating cellular processes and guiding cell
fate decisions has broad implications in tissue engineering, regenerative medicine, and cell …

Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane

E Sarikhani, V Patel, Z Li… - Advanced Functional …, 2024 - Wiley Online Library
Materials with engineered nano‐scale surface topographies, such as nanopillars,
nanoneedles, and nanowires, mimic natural structures like viral spike proteins, enabling …

Infrared spectroscopy of live cells using high-aspect-ratio metal-on-dielectric metasurfaces

A Mahalanabish, SH Huang, D Tulegenov… - Nano Letters, 2024 - ACS Publications
Fourier transform infrared (FTIR) spectroscopy is widely used for molecular analysis.
However, for the materials situated in an aqueous environment, a precondition for live …

Cross‐Scale Topography Achieved by MOPL with Positive Photoresist to Regulate the Cell Behavior

M Guo, XY Liu, T Li, Q Duan, XZ Dong, J Liu, F **… - Small, 2023 - Wiley Online Library
Cross‐scale micro‐nano structures play an important role in semiconductors, MEMS,
chemistry, and cell biology. Positive photoresist is widely used in lithography due to the …

Response of mesenchymal stem cells to surface topography of scaffolds and the underlying mechanisms

L **ao, Y Sun, L Liao, X Su - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Mesenchymal stem/stromal cells (MSCs) serve as essential components of regenerative
medicine. Their destiny is influenced by the interaction of the cells with the external …