Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020 - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Elastin-like polypeptides for biomedical applications

AK Varanko, JC Su, A Chilkoti - Annual review of biomedical …, 2020 - annualreviews.org
Elastin-like polypeptides (ELPs) are stimulus-responsive biopolymers derived from human
elastin. Their unique properties—including lower critical solution temperature phase …

[HTML][HTML] Elastin-like polypeptides as models of intrinsically disordered proteins

S Roberts, M Dzuricky, A Chilkoti - FEBS letters, 2015 - Elsevier
Elastin-like polypeptides (ELPs) are a class of stimuli-responsive biopolymers inspired by
the intrinsically disordered domains of tropoelastin that are composed of repeats of the …

Protein phase separation arising from intrinsic disorder: first-principles to bespoke applications

DM Shapiro, M Ney, SA Eghtesadi… - The Journal of Physical …, 2021 - ACS Publications
The phase separation of biomolecules has become the focus of intense research in the past
decade, with a growing body of research implicating this phenomenon in essentially all …

Elastin-like polypeptides in drug delivery

JC Rodríguez-Cabello, FJ Arias, MA Rodrigo… - Advanced drug delivery …, 2016 - Elsevier
The use of recombinant elastin-like materials, or elastin-like recombinamers (ELRs), in drug-
delivery applications is reviewed in this work. Although ELRs were initially used in similar …

Genetically encoded elastin‐like polypeptides for drug delivery

IC Jenkins, JJ Milligan, A Chilkoti - Advanced healthcare …, 2021 - Wiley Online Library
Elastin‐like polypeptides (ELPs) are thermally responsive biopolymers that consist of a
repeated amino acid motif derived from human tropoelastin. These peptides exhibit …

Applications of tunable resistive pulse sensing

E Weatherall, GR Willmott - Analyst, 2015 - pubs.rsc.org
Tunable resistive pulse sensing (TRPS) is an experimental technique that has been used to
study and characterise colloidal particles ranging from approximately 50 nm in diameter up …

Programmability and biomedical utility of intrinsically-disordered protein polymers

MC Giraldo-Castano, KA Littlejohn… - Advanced Drug Delivery …, 2024 - Elsevier
Intrinsically disordered proteins (IDPs) exhibit molecular-level conformational dynamics that
are functionally harnessed across a wide range of fascinating biological phenomena. The …

Engineering the architecture of elastin‐like polypeptides: from unimers to hierarchical self‐assembly

S Saha, S Banskota, S Roberts, N Kirmani… - Advanced …, 2020 - Wiley Online Library
Well‐defined tunable nanostructures formed through the hierarchical self‐assembly of
peptide building blocks have drawn significant attention due to their potential applications in …