Neuromodulation in epilepsy: state-of-the-art approved therapies

P Ryvlin, S Rheims, LJ Hirsch, A Sokolov… - The Lancet …, 2021 - thelancet.com
Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Towards network-guided neuromodulation for epilepsy

RJ Piper, RM Richardson, G Worrell, DW Carmichael… - Brain, 2022 - academic.oup.com
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Deep brain stimulation targets in epilepsy: systematic review and meta‐analysis of anterior and centromedian thalamic nuclei and hippocampus

A Vetkas, A Fomenko, J Germann, C Sarica… - …, 2022 - Wiley Online Library
Deep brain stimulation (DBS) is a neuromodulatory treatment used in patients with drug‐
resistant epilepsy (DRE). The primary goal of this systematic review and meta‐analysis is to …

[HTML][HTML] Deep brain stimulation of thalamus for epilepsy

RS Fisher - Neurobiology of Disease, 2023 - Elsevier
Neuromodulation (neurostimulation) is a relatively new and rapidly growing treatment for
refractory epilepsy. Three varieties are approved in the US: vagus nerve stimulation (VNS) …

Deep brain stimulation for drug‐resistant epilepsy

MCH Li, MJ Cook - Epilepsia, 2018 - Wiley Online Library
Objectives To review clinical evidence on the antiepileptic effects of deep brain stimulation
(DBS) for drug‐resistant epilepsy, its safety, and the factors influencing individual outcomes …

Deep brain stimulation and drug-resistant epilepsy: a review of the literature

N Zangiabadi, LD Ladino, F Sina… - Frontiers in …, 2019 - frontiersin.org
Introduction: Deep brain stimulation is a safe and effective neurointerventional technique for
the treatment of movement disorders. Electrical stimulation of subcortical structures may …

Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers

E Acerbo, A Jegou, C Luff, P Dzialecka… - Frontiers in …, 2022 - frontiersin.org
Introduction Neurostimulation applied from deep brain stimulation (DBS) electrodes is an
effective therapeutic intervention in patients suffering from intractable drug-resistant epilepsy …

Probabilistic map** of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

Deep brain stimulation for epilepsy

V Salanova - Epilepsy & Behavior, 2018 - Elsevier
The efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the
thalamus (ANT) for epilepsy (SANTE) trial was demonstrated by a randomized trial by Fisher …

Neuro-stimulation in focal epilepsy: A systematic review and meta-analysis

HC Skrehot, DJ Englot, Z Haneef - Epilepsy & Behavior, 2023 - Elsevier
Objectives Different neurostimulation modalities are available to treat drug-resistant focal
epilepsy when surgery is not an option including vagus nerve stimulation (VNS), responsive …