Cyclodextrin polymers: Structure, synthesis, and use as drug carriers

Z Liu, L Ye, J **, J Wang, Z Feng - Progress in Polymer Science, 2021 - Elsevier
Cyclodextrin-based polymers (CDPs) are amphiphilic macromolecules owing to their unique
structure and the presence of multiple hydroxyl groups. These polymers have become …

Cyclodextrin-based nanosponges: Overview and opportunities

G Utzeri, PMC Matias, D Murtinho… - Frontiers in …, 2022 - frontiersin.org
Nanosponges are solid cross-linked polymeric nano-sized porous structures. This broad
concept involves, among others, metal organic frameworks and hydrogels. The focus of this …

Cyclodextrins in drug delivery systems and their effects on biological barriers

Á Haimhoffer, Á Rusznyák, K Réti-Nagy… - Scientia …, 2019 - mdpi.com
Cyclodextrins are widely used excipients, composed of glucopyranose units with a cyclic
structure. One of their most important properties, is that their inner cavity is hydrophobic …

Cyclodextrin inclusion complexes for improved drug bioavailability and activity: synthetic and analytical aspects

Á Sarabia-Vallejo, MM Caja, AI Olives, MA Martín… - Pharmaceutics, 2023 - mdpi.com
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …

Formulation development, in vitro and in vivo evaluation of topical hydrogel formulation of econazole nitrate-loaded β-cyclodextrin nanosponges

S Srivastava, A Mahor, G Singh, K Bansal… - Journal of …, 2021 - Elsevier
Econazole nitrate, an antifungal drug used in the handling of skin ailments, is commercially
not efficient as these ailments typically require a more elevated concentration of the drug to …

Cyclodextrin nanosponge based hydrogel for the transdermal co-delivery of curcumin and resveratrol: Development, optimization, in vitro and ex vivo evaluation

R Pushpalatha, S Selvamuthukumar… - Journal of Drug Delivery …, 2019 - Elsevier
The present study aims at the design of the transdermal co-delivery of curcumin (CUR) and
resveratrol (RES) using cyclodextrin nanosponge based hydrogel. Cyclodextrin-based …

Biopharmaceutical and pharmacokinetic aspects of nanocarrier-mediated oral delivery of poorly soluble drugs

D Babadi, S Dadashzadeh, M Osouli… - Journal of Drug Delivery …, 2021 - Elsevier
Many new chemical entities have limited water solubility and therefore show low and/or
variable oral bioavailability. Among the various strategies to overcome this challenge …

Preparation and characterization of cyclodextrin nanosponges for organic toxic molecule removal

C Varan, A Anceschi, S Sevli, N Bruni, L Giraudo… - International journal of …, 2020 - Elsevier
Cyclodextrin-based nanosponges (CD-NS) are considered as safe and biocompatible
systems for removing toxic molecules from the body. Rapid removal of toxic molecules that …

Development of multi-compartment 3d-printed tablets loaded with self-nanoemulsified formulations of various drugs: A new strategy for personalized medicine

TA Ahmed, RI Felimban, HH Tayeb, WY Rizg… - Pharmaceutics, 2021 - mdpi.com
This work aimed to develop a three-dimensional printed (3DP) tablet containing glimepiride
(GLMP) and/or rosuvastatin (RSV) for treatment of dyslipidemia in patients with diabetes …

Exploring cyclodextrin-based nanosponges as drug delivery systems: Understanding the physicochemical factors influencing drug loading and release kinetics

B Pyrak, K Rogacka-Pyrak, T Gubica… - International Journal of …, 2024 - mdpi.com
Cyclodextrin-based nanosponges (CDNSs) are complex macromolecular structures
composed of individual cyclodextrins (CDs) and nanochannels created between cross …